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Amphocel 50mg Injection 1 Injection in 1 vial

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Amphocel 50mg Injection is a product of Intas Pharmaceuticals Ltd
Composition: Amphotericin B (50mg)

Pack of 1 injection

₹ 7142.86

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes
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All Details About Amphocel 50mg Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Amphocel 50mg Injection

Description:

Amphocel 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills the infection causing fungi and thus, treats the infection.

Amphocel 50mg Injection is administered as an injection by a healthcare professional. Compassionately do not self administer. Earlier you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood.

It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses:

Directions For Use:

Ordinary side effects of Amphocel

  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Chills
  • Headache
  • Anemia (low number of red blood cells)
  • Decreased potassium level in blood
  • Abnormal liver function tests
  • Decreased magnesium level in blood
  • Diarrhea
  • Decreased appetite
  • Hypotension (low blood pressure)
  • Skin rash
  • Nephrocalcinosis
  • Increased creatinine level in blood
  • Abnormal renal function tests
  • Renal tubular acidosis

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Warning & Precautions:

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amphocel 50mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Amphocel 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Amphocel 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amphocel 50mg Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amphocel 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amphocel 50mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amphocel 50mg Injection in patients with liver disease. Please consult your doctor.

FAQs:

Q. Is Amphocel 50mg Injection fungistatic or fungicidal?

Amphocel 50mg Injection is fungicidal in nature, it acts by killing the fungus

Q. Is Amphocel 50mg Injection light sensitive?

Amphocel 50mg Injection is not light sensitive

Q. What is Amphocel 50mg Injection liposomal?

Liposomal Amphocel 50mg Injection is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphocel 50mg Injection can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Amphocel 50mg Injection an antibiotic?

Affirmative, Amphocel 50mg Injection is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q. Is Amphocel 50mg Injection testing dose needed?

Affirmative, administration of Amphocel 50mg Injection is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q. How is Amphocel 50mg Injection administered?

Amphocel 50mg Injection is either administered as intravenous injection or infusion by a registered medical professional only

Q. How does Amphocel 50mg Injection cause nephrotoxicity and hyperkalemia?

Amphocel 50mg Injection can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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