Solonex Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.
Solonex Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification.
Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Peripheral neuropathy (tingling and numbness of feet and hand)
Hepatitis (viral infection of liver)
Skin rash
Lethargy
Increased liver enzymes
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youβre worried about them
Warning & Precautions:
Alcohol
UNSAFE
Consuming alcohol while taking Solonex Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Solonex Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Solonex Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Solonex Tablet may cause side effects which could affect your ability to drive. Solonex Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Solonex Tablet is safe to use in patients with kidney disease. No dose adjustment of Solonex Tablet is recommended. However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Solonex Tablet should be used with caution in patients with liver disease. Dose adjustment of Solonex Tablet may be needed. Please consult your doctor. Employ of Solonex Tablet is not recommended in patients with severe liver disease.
FAQs:
Q. Is Solonex Tablet an antibiotic?
Solonex Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Q. Is Solonex Tablet chemotherapy/chemotherapy drug?
Solonex Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Q. Is Solonex Tablet bacteriostatic or bactericidal?
Solonex Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Q. Is Solonex Tablet safe?
Affirmative. Solonex Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Solonex Tablet a MAOI?
Solonex Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
Q. Is Solonex Tablet a sulfa drug?
No. The chemical structure and mechanism of action of Solonex Tablet is different from sulfa drugs
Q. Is Solonex Tablet an inducer or inhibitor?
Solonex Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Solonex Tablet cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Alters in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Solonex Tablet. You may experience few of these side effects while on multi drug (including Solonex Tablet) treatment for tuberculosis
Q. Does Solonex Tablet cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Solonex Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Solonex Tablet affect birth control?
Solonex Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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