ENDAce OS 40mg Oral Suspension 120.0 ml in 1 bottle

Last Updated: March 27th, 2026

ENDAce OS 40mg Oral Suspension is a product of Samarth Life Sciences Pvt Ltd

Composition: Megestrol (40mg)

Pack of 120 ml

₹ 3375.00

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About ENDAce OS 40mg Oral Suspension

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about ENDAce OS 40mg Oral Suspension

Description:

ENDAce OS 40mg Oral Suspension is a medicine used for the treatment of anorexia, cachexia, or significant, unexplained weight loss in patients with advanced cancer or acquired immunodeficiency syndrome (AIDS). It helps improve appetite and promote weight gain.

ENDAce OS 40mg Oral Suspension may be taken with or without food. Take it exactly as prescribed by your doctor. Your doctor will decide how much you need to take and for how long. Take it regularly and at the same time each day. Do not stop taking it suddenly without your doctor’s advice.

Ordinary side effects of ENDAce OS 40mg Oral Suspension include diarrhea, rash, nausea, vomiting, headache, weakness (asthenia), and high blood pressure. If any of these side effects persist or worsen, stop the medicine and inform your doctor promptly. Managing side effects may involve dose adjustments, monitoring blood sugar closely, and supportive treatment as advised by your doctor.

ENDAce OS 40mg Oral Suspension should not be used in patients who are allergic to megestrol acetate or any component in the product. It is contraindicated in known or suspected pregnancy because it may cause harm to the unborn baby. Women of childbearing age should use effective contraception during treatment. Nursing mothers should discontinue breastfeeding if treatment is required. Elderly patients and those with kidney problems may require careful dose selection and monitoring.

Long-term use may affect the body’s adrenal gland function and can lead to adrenal insufficiency, especially during stress such as surgery or serious illness. It may also worsen existing diabetes or cause new-onset diabetes. Caution is advised in patients with a history of blood clots, as thromboembolic events such as thrombophlebitis or pulmonary embolism have been reported.

Uses:

Treatment of Anorexia
Treatment of Cachexia
Treatment of significant unexplained Weight loss

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. ENDAce OS 40mg Oral Suspension may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of ENDAce

Nausea
Diarrhea
Impotence
Rash
Flatulence
High blood pressure
Weakness

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with ENDAce OS 40mg Oral Suspension. Please consult your doctor.

Pregnancy

UNSAFE

ENDAce OS 40mg Oral Suspension is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

ENDAce OS 40mg Oral Suspension is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether ENDAce OS 40mg Oral Suspension alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

ENDAce OS 40mg Oral Suspension should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of ENDAce OS 40mg Oral Suspension in patients with liver disease.

FAQs:

What is ENDAce OS 40mg Oral Suspension used for?

ENDAce OS 40mg Oral Suspension is used for the treatment of anorexia, cachexia, or unexplained, significant weight loss in patients with cancer or acquired immunodeficiency syndrome (AIDS). These conditions involve poor appetite and progressive weight loss associated with serious illness. The medicine helps improve appetite and support weight gain in affected patients.

How does ENDAce OS 40mg Oral Suspension help with weight gain?

ENDAce OS 40mg Oral Suspension works by stimulating appetite, which helps increase food intake. The exact mechanism by which it improves appetite and body weight is not fully understood. Its hormonal activity is believed to influence appetite regulation, leading to gradual weight gain in some patients.

How long does it take to see results?

Improvements in appetite and weight gain have been observed within weeks in clinical studies, although response varies between individuals. Some patients may notice appetite improvement earlier than weight gain. Regular follow-up with your doctor is important to assess treatment response.

Can ENDAce OS 40mg Oral Suspension affect blood sugar levels?

Affirmative, ENDAce OS 40mg Oral Suspension has been associated with new-onset diabetes and worsening of preexisting diabetes. It may increase blood glucose levels, particularly with long-term use. Tolerants with diabetes should monitor their blood sugar closely and inform their doctor of any unusual symptoms, such as increased thirst or frequent urination.

Can ENDAce OS 40mg Oral Suspension affect the adrenal glands?

Affirmative, long-term use of ENDAce OS 40mg Oral Suspension may suppress adrenal gland function. Cases of adrenal insufficiency have been reported, especially during stress such as surgery or infection. Symptoms like weakness, dizziness, nausea, or low blood pressure should be reported promptly.

Is ENDAce OS 40mg Oral Suspension safe during pregnancy?

ENDAce OS 40mg Oral Suspension is contraindicated in known or suspected pregnancy because it may cause harm to the unborn baby. Women of childbearing potential should use effective contraception while taking this medicine. If pregnancy occurs during treatment, the doctor should be informed immediately.

Can ENDAce OS 40mg Oral Suspension increase the risk of blood clots?

Affirmative, thromboembolic events such as thrombophlebitis and pulmonary embolism have been reported with ENDAce OS 40mg Oral Suspension use. Tolerants with a history of blood clots should use the medicine with caution. Perceivek immediate medical care if you experience chest pain, shortness of breath, or swelling in one leg.

Is ENDAce OS 40mg Oral Suspension meant to prevent weight loss before it happens?

No, ENDAce OS 40mg Oral Suspension is not intended for prophylactic use to avoid weight loss. It is prescribed only after significant weight loss, anorexia, or cachexia has developed. The medicine should be used under medical supervision after appropriate evaluation.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

Disclaimer:

Getomeds primary intention is to ensure that its consumers get information that is reviewed by experts, accurate, and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all of your concerns about any disease or medication. Do not disregard or postpone seeking professional medical advice because of something you read on Getomeds. Our mission is to support, not replace, the doctor-patient relationship.