Adestrol 40mg Tablet 10.0 tablets in 1 strip

Last Updated: December 8th, 2025

Adestrol 40mg Tablet is a product of Adley Formulations

Composition: Megestrol (40mg)

Pack of 10 tablet

₹ 140.63

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Limited Stock

All Details About Adestrol 40mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Adestrol 40mg Tablet

Description:

Adestrol 40mg Tablet is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV.

Adestrol 40mg Tablet should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include weight gain, increase in appetite, shortness of breath, hot flushes (warm face and neck), high blood pressure, and constipation. Most of these are temporary, and go away as soon as the body adjusts to the treatment. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine. Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adestrol 40mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Adestrol

Increased appetite
Weight gain
Hot flashes
High blood pressure
Constipation

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Adestrol 40mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Adestrol 40mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Adestrol 40mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CAUTION

Adestrol 40mg Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

CAUTION

Adestrol 40mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Adestrol 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

FAQs:

What is Adestrol 40mg Tablet and what is it used for?

Adestrol 40mg Tablet contains a medicine called Megestrol which is similar to the hormone progesterone, that naturally occurs in your body. It is used in hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.

Does Adestrol 40mg Tablet make you gain weight?

Affirmative, Adestrol 40mg Tablet may cause weight gain as a very common side effect. Weight gain could be due to an increase in appetite which leads to an overall increase in fat and body cell mass. Consult your doctor if you experience excessive weight gain. It is commonly used to treat malnutrition, loss of appetite and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). However, it is not intended for preventive use to avoid weight loss.

When should I take Adestrol 40mg Tablet?

You can take Adestrol 40mg Tablet at any time of the day. However, you should take it exactly as prescribed by your doctor. Swallow it whole with a glass of water. It can be taken with or without food, preferably at the same time each day since this helps you to remember taking it. Check with your doctor if you are not sure.

Does Adestrol 40mg Tablet stop periods?

No, Adestrol 40mg Tablet does not stop periods. However, it may interfere with your normal menstrual cycle. It may cause break-through bleeding and therefore has limited use in HIV infected women. Consult your doctor in case you experience breakthrough bleeding during the treatment with Adestrol 40mg Tablet.

Is Adestrol 40mg Tablet a chemo medicine?

No, Adestrol 40mg Tablet is not a chemo medicine. It is a man-made version of the progesterone hormone. It is helpful in the treatment of breast cancer and endometrial cancer (cancer of the uterus). It works by modifying the female hormones involved in cancer growth.

Is Adestrol 40mg Tablet acetate safe to be taken during pregnancy?

No, you should not take Adestrol 40mg Tablet if you are pregnant or are planning a pregnancy. However, if you become pregnant while taking Adestrol 40mg Tablet, immediately contact your doctor as Adestrol 40mg Tablet may cause harm to your unborn baby. It is important to inform the doctor because it may cause abnormalities of sex organs in male and female babies if it is taken during first 3 months of pregnancy. Usually, the doctor may suggest a pregnancy test before starting your treatment with Adestrol 40mg Tablet.

Does Adestrol 40mg Tablet prevent pregnancy?

No, Adestrol 40mg Tablet does not prevent pregnancy. It may disrupt your normal menstrual cycle but does not prevent pregnancy. Hence, you should use a reliable method of birth control to prevent pregnancy. Check with your doctor in case you are not sure or have any doubts.

What is Adestrol 40mg Tablet? What is it used for?

Adestrol 40mg Tablet contains Megestrol, which is similar to the naturally produced hormone progesterone. The medicine is used in treatment hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.

Does Adestrol 40mg Tablet need to be refrigerated?

No, there is no need to refrigerate Adestrol 40mg Tablet. However, this medicine should not be stored above 25°C. It should be stored in original packaging to protect from moisture.

Is Adestrol 40mg Tablet used for hot flashes?

Employ of Adestrol 40mg Tablet in hot flashes is not approved. Forever consult your doctor before using Adestrol 40mg Tablet. Usually, estrogen in women and androgen in men are used for the treatment of hot flashes but these hormones cannot be used in females with breast cancer and males with prostate cancer.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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