Egistral 40mg Tablet 10.0 tablets in 1 strip

Last Updated: March 25th, 2026

Egistral 40mg Tablet is a product of Aaltramed Healthcare Ltd

Composition: Megestrol (40mg)

Pack of 10 tablet

₹ 46.83

Check for the Availability! Please do contact!

Limited Stock

All Details About Egistral 40mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Egistral 40mg Tablet

Description:

Egistral 40mg Tablet is a medicine used for the treatment of anorexia, cachexia, or significant, unexplained weight loss in patients with advanced cancer or acquired immunodeficiency syndrome (AIDS). It helps improve appetite and promote weight gain.

Egistral 40mg Tablet may be taken with or without food. Take it exactly as prescribed by your doctor. Your doctor will decide how much you need to take and for how long. Take it regularly and at the same time each day. Do not stop taking it suddenly without your doctor’s advice.

Ordinary side effects of Egistral 40mg Tablet include diarrhea, rash, nausea, vomiting, headache, weakness (asthenia), and high blood pressure. If any of these side effects persist or worsen, stop the medicine and inform your doctor promptly. Managing side effects may involve dose adjustments, monitoring blood sugar closely, and supportive treatment as advised by your doctor.

Egistral 40mg Tablet should not be used in patients who are allergic to megestrol acetate or any component in the product. It is contraindicated in known or suspected pregnancy because it may cause harm to the unborn baby. Women of childbearing age should use effective contraception during treatment. Nursing mothers should discontinue breastfeeding if treatment is required. Elderly patients and those with kidney problems may require careful dose selection and monitoring.

Long-term use may affect the body’s adrenal gland function and can lead to adrenal insufficiency, especially during stress such as surgery or serious illness. It may also worsen existing diabetes or cause new-onset diabetes. Caution is advised in patients with a history of blood clots, as thromboembolic events such as thrombophlebitis or pulmonary embolism have been reported.

Uses:

Treatment of Anorexia
Treatment of Cachexia
Treatment of significant unexplained Weight loss

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Egistral 40mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Egistral

Nausea
Diarrhea
Impotence
Rash
Flatulence
High blood pressure
Weakness

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Egistral 40mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Egistral 40mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Egistral 40mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Egistral 40mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Egistral 40mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Egistral 40mg Tablet in patients with liver disease.

FAQs:

What is Egistral 40mg Tablet used for?

Egistral 40mg Tablet is used for the treatment of anorexia, cachexia, or unexplained, significant weight loss in patients with cancer or acquired immunodeficiency syndrome (AIDS). These conditions involve poor appetite and progressive weight loss associated with serious illness. The medicine helps improve appetite and support weight gain in affected patients.

How does Egistral 40mg Tablet help with weight gain?

Egistral 40mg Tablet works by stimulating appetite, which helps increase food intake. The exact mechanism by which it improves appetite and body weight is not fully understood. Its hormonal activity is believed to influence appetite regulation, leading to gradual weight gain in some patients.

How long does it take to see results?

Improvements in appetite and weight gain have been observed within weeks in clinical studies, although response varies between individuals. Some patients may notice appetite improvement earlier than weight gain. Regular follow-up with your doctor is important to assess treatment response.

Can Egistral 40mg Tablet affect blood sugar levels?

Affirmative, Egistral 40mg Tablet has been associated with new-onset diabetes and worsening of preexisting diabetes. It may increase blood glucose levels, particularly with long-term use. Tolerants with diabetes should monitor their blood sugar closely and inform their doctor of any unusual symptoms, such as increased thirst or frequent urination.

Can Egistral 40mg Tablet affect the adrenal glands?

Affirmative, long-term use of Egistral 40mg Tablet may suppress adrenal gland function. Cases of adrenal insufficiency have been reported, especially during stress such as surgery or infection. Symptoms like weakness, dizziness, nausea, or low blood pressure should be reported promptly.

Is Egistral 40mg Tablet safe during pregnancy?

Egistral 40mg Tablet is contraindicated in known or suspected pregnancy because it may cause harm to the unborn baby. Women of childbearing potential should use effective contraception while taking this medicine. If pregnancy occurs during treatment, the doctor should be informed immediately.

Can Egistral 40mg Tablet increase the risk of blood clots?

Affirmative, thromboembolic events such as thrombophlebitis and pulmonary embolism have been reported with Egistral 40mg Tablet use. Tolerants with a history of blood clots should use the medicine with caution. Perceivek immediate medical care if you experience chest pain, shortness of breath, or swelling in one leg.

Is Egistral 40mg Tablet meant to prevent weight loss before it happens?

No, Egistral 40mg Tablet is not intended for prophylactic use to avoid weight loss. It is prescribed only after significant weight loss, anorexia, or cachexia has developed. The medicine should be used under medical supervision after appropriate evaluation.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

Disclaimer:

Getomeds primary intention is to ensure that its consumers get information that is reviewed by experts, accurate, and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all of your concerns about any disease or medication. Do not disregard or postpone seeking professional medical advice because of something you read on Getomeds. Our mission is to support, not replace, the doctor-patient relationship.