Coflam MR 400mg/325mg/250mg Tablet 10.0 tablets in 1 strip

Last Updated: March 24th, 2026

Coflam MR 400mg/325mg/250mg Tablet is a product of Parasol Laboratories

Composition: Ibuprofen (400mg) + Paracetamol (325mg) + Chlorzoxazone (250mg)

Pack of 10 tablet

₹ 32.81

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All Details About Coflam MR 400mg/325mg/250mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Coflam MR 400mg/325mg/250mg Tablet

Description:

Coflam MR 400mg/325mg/250mg Tablet is a combination medicine used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Coflam MR 400mg/325mg/250mg Tablet may be prescribed alone or in combination with another medicine. It should be taken with food. This will prevent you from getting an upset stomach. You should take it strictly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Using this medicine may cause common side effects such as nausea, indigestion, stomach pain, weakness, dizziness, and sleepiness. If you experienced any such side effects that do not resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent them.

The medicine may not be suitable for everybody. Earlier taking it, let your doctor know if you have any medical conditions or disorders. Let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors first before using the medicine.

Uses:

Treatment of Pain due to muscle spasm

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coflam MR 400mg/325mg/250mg Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Coflam

Nausea
Indigestion
Stomach pain
Weakness
Dizziness
Sleepiness
Heartburn

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Coflam MR 400mg/325mg/250mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Coflam MR 400mg/325mg/250mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Coflam MR 400mg/325mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Coflam MR 400mg/325mg/250mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Coflam MR 400mg/325mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Employ of Coflam MR 400mg/325mg/250mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.

Liver

CAUTION

Coflam MR 400mg/325mg/250mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Coflam MR 400mg/325mg/250mg Tablet is not recommended in patients with severe liver disease and active liver disease.

FAQs:

What is Coflam MR 400mg/325mg/250mg Tablet?

Coflam MR 400mg/325mg/250mg Tablet is a combination of three medicines: Ibuprofen, Paracetamol and Chlorzoxazone. This medication helps in relieving muscle pain. It works by relaxing the muscles by acting upon the central nervous system and lowering chemical substance in the body which causes muscle pain.

Can the Coflam MR 400mg/325mg/250mg Tablet be stopped when pain is relieved?

Coflam MR 400mg/325mg/250mg Tablet is usually used for short term and can be discontinued when the pain is relieved. However, Coflam MR 400mg/325mg/250mg Tablet should be continued if the doctor has advised to do so.

Can the use of Coflam MR 400mg/325mg/250mg Tablet cause nausea and vomiting?

Affirmative, the use of Coflam MR 400mg/325mg/250mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Communicate to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

Can the use of Coflam MR 400mg/325mg/250mg Tablet cause dizziness?

Affirmative, the use of Coflam MR 400mg/325mg/250mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded it is better to rest for some time and resume once you feel better.

Are there any specific contraindications associated with the use of Coflam MR 400mg/325mg/250mg Tablet?

The use of Coflam MR 400mg/325mg/250mg Tablet is considered to be harmful for patients with known allergy to painkiller (NSAIDS) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcer or in patients with active or recurrent stomach ulcer / bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Can the Coflam MR 400mg/325mg/250mg Tablet be used with Vitamin B-complex?

Affirmative, Coflam MR 400mg/325mg/250mg Tablet can be taken with Vitamin B-complex preparations. While Coflam MR 400mg/325mg/250mg Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.

Can Coflam MR 400mg/325mg/250mg Tablet cause addiction?

No, there is no report of any patient getting addicted to Coflam MR 400mg/325mg/250mg Tablet.

Can the use of Coflam MR 400mg/325mg/250mg Tablet cause damage to kidneys?

Affirmative, the long-term use of Coflam MR 400mg/325mg/250mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Employ of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Employ of painkillers is not recommended to patients with underlying kidney disease.

Will Coflam MR 400mg/325mg/250mg Tablet be more effective if taken in higher doses?

No, taking more of this medicine will not make it more effective, rather it can lead to increased side effects. If the symptoms are getting severe, please consult the doctor for re-evaluation.

What is the recommended storage condition for Coflam MR 400mg/325mg/250mg Tablet?

Retain this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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