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All Details About Wirox Injection
Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Wirox Injection
Description:
Wirox Injection is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.Wirox Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Earlier using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses:
Directions For Use:
Your doctor or nurse will give you this medicine. Compassionately do not self administer.Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themOrdinary side effects of Wirox
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
Warning & Precautions:
Alcohol
CAUTION
Caution is advised when consuming alcohol with Wirox Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Wirox Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Wirox Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Wirox Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Wirox Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Wirox Injection may be needed. Please consult your doctor.
Liver
CAUTION
Wirox Injection should be used with caution in patients with liver disease. Dose adjustment of Wirox Injection may be needed. Please consult your doctor.
FAQs:
What is the difference between Wirox Injection and diclofenac?
Both Wirox Injection and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Wirox Injection.
What is the difference between Wirox Injection and naproxen?
Both Wirox Injection and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Wirox Injection.
What is the difference between Wirox Injection and meloxicam?
Both Wirox Injection and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Wirox Injection.
What is the difference between Wirox Injection and ketoprofen?
Both Wirox Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Wirox Injection. Ketoprofen gel also showed excellent tolerability.
What is the difference between Wirox Injection and tramadol?
Wirox Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
What is the difference between Wirox Injection and nimesulide?
Both Wirox Injection and nimesulide are pain killers. However, Wirox Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can Wirox Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Wirox Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Wirox Injection.
Are Wirox Injection and aspirin same?
No. Wirox Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Wirox Injection be used along with dexamethasone?
No. Wirox Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Can Wirox Injection be used with methocarbamol?
Affirmative. Methocarbamol can be used with Wirox Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Can Wirox Injection be used along with paracetamol?
Affirmative. Paracetamol can be used with Wirox Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Is Wirox Injection a NSAID?
Affirmative. Wirox Injection is a non-steroidal anti-inflammatory drug (NSAID).
Is Wirox Injection a sulfa drug?
Wirox Injection is a sulphur containing compound. Wirox Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Is Wirox Injection a blood thinner?
No. Wirox Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Is Wirox Injection a muscle relaxant?
No. Wirox Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Is Wirox Injection a narcotic?
No. Wirox Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Can Wirox Injection be used in hypertension?
No. Wirox Injection is not a medication to control hypertension. It is important to note that Wirox Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Wirox Injection.
Can Wirox Injection be used along with Losartan?
No. Wirox Injection should not be combined with Losartan. It is important to note that Wirox Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Wirox Injection.
Can Wirox Injection be used with Lisinopril?
No. Wirox Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Wirox Injection.
Can Wirox Injection be used with calcium channel blocker?
Affirmative. Wirox Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Can Wirox Injection be used with Tizanidine?
Affirmative, Wirox Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Why is beta cyclodextrin added to Wirox Injection?
Affirmative. Wirox Injection can be combined with beta-cyclodextrin. Research has shown that combining Wirox Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Are there any alternatives of Wirox Injection?
Affirmative. There are alternatives to Wirox Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
What are the contraindications for Wirox Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Can Wirox Injection be used in the treatment of allergy?
No. Wirox Injection is not a drug to treat allergy. It is a pain killer.
How long does Wirox Injection work?
Wirox Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can you get high by using Wirox Injection?
No. Wirox Injection is not known to cause high. It is a non-narcotic painkiller.
Can Wirox Injection be used to treat menstrual cramp?
Wirox Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Can I use Wirox Injection for a migraine?
Wirox Injection is not approved for the treatment of migraine. Research studies have shown that Wirox Injection is effective in significantly decreasing the pain associated with migraine without aura.
Is Wirox Injection effective in back pain management?
Affirmative. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Wirox Injection as the cause of back pain can be different for different person.
Is Wirox Injection affective in gout management?
Affirmative. Wirox Injection can be given for the treatment of acute gout. Research studies have shown Wirox Injection to be highly effective in the treatment of acute gout.
Can you donate blood when on the medication with Wirox Injection?
Affirmative. You can donate blood when on Wirox Injection. Do inform your doctor before donating blood.
Can I use Wirox Injection if I am a diabetic?
Wirox Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Wirox Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Can I use Wirox Injection if I have a deranged renal function?
No. Wirox Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Can Wirox Injection lead to skin reactions?
Affirmative. Wirox Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Can I use Wirox Injection if I am pregnant?
No. Wirox Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can I use Wirox Injection if I have peptic ulcer disease?
No. Wirox Injection is contraindicated in cases of active peptic ulcer disease. Wirox Injection is known to cause gastric ulceration and bleeding.
Can I use Wirox Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Can Wirox Injection lead to difficulty in conception?
Affirmative. Wirox Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Can Wirox Injection be used with diuretics?
No. Wirox Injection should not be used with diuretics. Wirox Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can Wirox Injection be used with lithium?
No. Wirox Injection should not be used with lithium. Wirox Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Wirox Injection be used with warfarin?
No. Wirox Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
What increases the chances of getting a gastric ulcer when I am already taking Wirox Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Wirox Injection?
Tolerants who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
What are the serious side effects of Wirox Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Written by:
Dr. Lokanish
M.B.B.S.
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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