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All Details About Doloxicam Tablet
Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Doloxicam Tablet
Description:
Doloxicam Tablet is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.Doloxicam Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Earlier using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Uses:
Directions For Use:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doloxicam Tablet is to be taken with food.Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themOrdinary side effects of Doloxicam
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
Warning & Precautions:
Alcohol
UNSAFE
It is unsafe to consume alcohol with Doloxicam Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Doloxicam Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Doloxicam Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Doloxicam Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Doloxicam Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Doloxicam Tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Doloxicam Tablet should be used with caution in patients with liver disease. Dose adjustment of Doloxicam Tablet may be needed. Please consult your doctor.
FAQs:
Q. What is the difference between Doloxicam Tablet and diclofenac?
Both Doloxicam Tablet and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Doloxicam Tablet.
Q. What is the difference between Doloxicam Tablet and naproxen?
Both Doloxicam Tablet and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Doloxicam Tablet.
Q. What is the difference between Doloxicam Tablet and meloxicam?
Both Doloxicam Tablet and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Doloxicam Tablet.
Q. What is the difference between Doloxicam Tablet and ketoprofen?
Both Doloxicam Tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Doloxicam Tablet. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Doloxicam Tablet and tramadol?
Doloxicam Tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Doloxicam Tablet and nimesulide?
Both Doloxicam Tablet and nimesulide are pain killers. However, Doloxicam Tablet is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Doloxicam Tablet be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Doloxicam Tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Doloxicam Tablet.
Q. Are Doloxicam Tablet and aspirin same?
No. Doloxicam Tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Doloxicam Tablet be used along with dexamethasone?
No. Doloxicam Tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Doloxicam Tablet be used with methocarbamol?
Affirmative. Methocarbamol can be used with Doloxicam Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Doloxicam Tablet be used along with paracetamol?
Affirmative. Paracetamol can be used with Doloxicam Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Doloxicam Tablet a NSAID?
Affirmative. Doloxicam Tablet is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Doloxicam Tablet a sulfa drug?
Doloxicam Tablet is a sulphur containing compound. Doloxicam Tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Doloxicam Tablet a blood thinner?
No. Doloxicam Tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Doloxicam Tablet a muscle relaxant?
No. Doloxicam Tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Doloxicam Tablet a narcotic?
No. Doloxicam Tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Doloxicam Tablet be used in hypertension?
No. Doloxicam Tablet is not a medication to control hypertension. It is important to note that Doloxicam Tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Doloxicam Tablet.
Q. Can Doloxicam Tablet be used along with Losartan?
No. Doloxicam Tablet should not be combined with Losartan. It is important to note that Doloxicam Tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloxicam Tablet.
Q. Can Doloxicam Tablet be used with Lisinopril?
No. Doloxicam Tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloxicam Tablet.
Q. Can Doloxicam Tablet be used with calcium channel blocker?
Affirmative. Doloxicam Tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Doloxicam Tablet be used with Tizanidine?
Affirmative, Doloxicam Tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Doloxicam Tablet?
Affirmative. Doloxicam Tablet can be combined with beta-cyclodextrin. Research has shown that combining Doloxicam Tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Doloxicam Tablet?
Affirmative. There are alternatives to Doloxicam Tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Doloxicam Tablet?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Doloxicam Tablet be used in the treatment of allergy?
No. Doloxicam Tablet is not a drug to treat allergy. It is a pain killer.
Q. How long does Doloxicam Tablet work?
Doloxicam Tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Doloxicam Tablet?
No. Doloxicam Tablet is not known to cause high. It is a non-narcotic painkiller.
Q. Can Doloxicam Tablet be used to treat menstrual cramp?
Doloxicam Tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Doloxicam Tablet for a migraine?
Doloxicam Tablet is not approved for the treatment of migraine. Research studies have shown that Doloxicam Tablet is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Doloxicam Tablet effective in back pain management?
Affirmative. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Doloxicam Tablet as the cause of back pain can be different for different person.
Q. Is Doloxicam Tablet affective in gout management?
Affirmative. Doloxicam Tablet can be given for the treatment of acute gout. Research studies have shown Doloxicam Tablet to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Doloxicam Tablet?
Affirmative. You can donate blood when on Doloxicam Tablet. Do inform your doctor before donating blood.
Q. Can I use Doloxicam Tablet if I am a diabetic?
Doloxicam Tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Doloxicam Tablet so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Doloxicam Tablet if I have a deranged renal function?
No. Doloxicam Tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Doloxicam Tablet lead to skin reactions?
Affirmative. Doloxicam Tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Doloxicam Tablet if I am pregnant?
No. Doloxicam Tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Doloxicam Tablet if I have peptic ulcer disease?
No. Doloxicam Tablet is contraindicated in cases of active peptic ulcer disease. Doloxicam Tablet is known to cause gastric ulceration and bleeding.
Q. Can I use Doloxicam Tablet if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Doloxicam Tablet lead to difficulty in conception?
Affirmative. Doloxicam Tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Doloxicam Tablet be used with diuretics?
No. Doloxicam Tablet should not be used with diuretics. Doloxicam Tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Doloxicam Tablet be used with lithium?
No. Doloxicam Tablet should not be used with lithium. Doloxicam Tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Doloxicam Tablet be used with warfarin?
No. Doloxicam Tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Doloxicam Tablet?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Doloxicam Tablet?
Tolerants who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Doloxicam Tablet?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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