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Tilpazan Solution for Injection

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Tilpazan Solution for Injection is a product of Lupin Ltd
Composition: Inclisiran (284mg)

₹ 120000.00

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes
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All Details About Tilpazan Solution for Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Tilpazan Solution for Injection

Description:

Tilpazan Solution for Injection is a medicine used alongside a healthy diet and statin therapy to help lower cholesterol levels in adults with heart disease. Cholesterol is a fatty substance that builds up in the blood vessels and causes narrowing. Lowering cholesterol levels reduces the risk of heart attack and stroke.

Tilpazan Solution for Injection is administered subcutaneously into the abdomen, upper arm, or thigh. Do not inject in areas of active skin disease or injury, such as sunburns, rashes, inflammation, or skin infections. A doctor or a nurse generally administers it, and it should not be self-administered at home.


It is important to have your cholesterol levels checked regularly. This medicine is only one part of a treatment program, which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods high in fat.


Ordinary side effects of this medicine include injection site reactions, joint pain, urinary tract infection, diarrhea, bronchitis, pain in extremities, and shortness of breath. Earlier taking it, let your doctor know if you are suffering from any liver or kidney disease. Pregnant and breastfeeding women should consult the doctor before taking this medicine.

Uses:

Directions For Use:

Your doctor or nurse will guide you how to use this medicine.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Tilpazan

  • Pain in extremities
  • Pantingness
  • Joint pain
  • Injection site reactions (pain, swelling, redness)
  • Urinary tract infection
  • Diarrhea
  • Bronchitis (inflammation of the airways)

Warning & Precautions:

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tilpazan Solution for Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Tilpazan Solution for Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Tilpazan Solution for Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Tilpazan Solution for Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Tilpazan Solution for Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver
CAUTION
Tilpazan Solution for Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is Tilpazan Solution for Injection, and how does it work?

Tilpazan Solution for Injection is a prescription cholesterol-lowering medication used in adults with high LDL cholesterol. It works by helping the liver remove more bad LDL cholesterol from the blood. Tilpazan Solution for Injection blocks a protein called PCSK9, which allows the liver to absorb and break down more LDL cholesterol and remove it from the blood.

How often is Tilpazan Solution for Injection given?

Tilpazan Solution for Injection is given as a subcutaneous injection (under the skin) by a healthcare professional. You get one dose at the start, another at 3 months, and then one injection every 6 months, making it a biannual cholesterol treatment.

Is Tilpazan Solution for Injection safe for people with kidney or liver problems?

Affirmative, Tilpazan Solution for Injection is generally safe for people with mild to moderate kidney or liver disease. However, if you have severe kidney or liver issues, your doctor will monitor you more closely. No dose changes are usually needed.

What should I do if I miss the Tilpazan Solution for Injection?

If your next Tilpazan Solution for Injection due is less than 3 months late, take it as soon as possible and continue your usual schedule. If it is more than 3 months late, your doctor will restart your treatment schedule.

What are the serious warnings or precautions for Tilpazan Solution for Injection?

The serious side effects of Tilpazan Solution for Injection are rare, but you should not take Tilpazan Solution for Injection if you are allergic to any of its ingredients. If you have severe liver or kidney issues, your doctor will decide if it is right for you.

How long does Tilpazan Solution for Injection take to lower LDL cholesterol?

Tilpazan Solution for Injection begins working within 14 days, and the full cholesterol-lowering effect is usually seen within 30 to 60 days after injection. Its effects are long-lasting, with LDL cholesterol still reduced after 6 months.

How does Tilpazan Solution for Injection differ from other cholesterol-lowering treatments?

Unlike daily oral medications, Tilpazan Solution for Injection requires only two to three injections per year, which may improve adherence for some patients. It works by targeting the production of PCSK9 in the liver. This way, the liver's ability to remove low-density lipoprotein cholesterol (LDL-C) from the blood is increased, offering an alternative mechanism for lowering LDL-C compared to other treatments.

Is Tilpazan Solution for Injection suitable for everyone with high cholesterol?

Tilpazan Solution for Injection is intended for adults who have not reached their cholesterol goals with lifestyle changes and maximum tolerated statin medication therapy. It is not recommended for individuals with certain conditions or those who are pregnant or breastfeeding. Consult your doctor to determine if Tilpazan Solution for Injection is right for you.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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