Pazliz 400 Tablet 30.0 tablets in 1 bottle

Last Updated: December 13th, 2025

Pazliz 400 Tablet is a product of Khandelwal Laboratories Pvt Ltd

Composition: Pazopanib (400mg)

Pack of 30 tablet

₹ 9468.75

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Pazliz 400 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Pazliz 400 Tablet

Description:

Pazliz 400 Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.

Pazliz 400 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea and high blood pressure are the most common side effects of this medicine. Doctor may advise for regular monitoring of your blood pressure while on treatment. Drink plenty of fluids to overcome diarrhea or consult with your doctor if it bothers you. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you experience fever, flu-like symptoms and shortness of breath.

Earlier taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pazliz 400 Tablet is to be taken empty stomach.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Pazliz

High blood pressure
Decreased appetite
Weight loss
Taste change
Abnormal skin pigmentation
Hair discoloration
Tumor pain
Pantingness
Headache
Nausea
Vomiting
Musculoskeletal (bone, muscle or joint) pain
Chubbyigue
Alter in color of hair
Diarrhea

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pazliz 400 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Pazliz 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Pazliz 400 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Pazliz 400 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Pazliz 400 Tablet is safe to use in patients with kidney disease. No dose adjustment of Pazliz 400 Tablet is recommended.

Liver

CAUTION

Pazliz 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pazliz 400 Tablet may be needed. Please consult your doctor.
Employ of Pazliz 400 Tablet is not advised in patients with moderate to severe liver disease.

FAQs:

Is Pazliz 400 Tablet a chemotherapy medicine?

Pazliz 400 Tablet is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazliz 400 Tablet works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

How should I take Pazliz 400 Tablet?

Pazliz 400 Tablet should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Can Pazliz 400 Tablet be taken with food?

Pazliz 400 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

How will I know if Pazliz 400 Tablet is helping me?

The duration for which you have to continue taking Pazliz 400 Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Are there any food restrictions while I’m taking Pazliz 400 Tablet?

Affirmative, it is best to avoid grapefruit and grapefruit juice while on Pazliz 400 Tablet, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

How long I have to take Pazliz 400 Tablet?

What is the most important information I need to know about Pazliz 400 Tablet?

Pazliz 400 Tablet may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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