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Pazobrite 400 Tablet

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Pazobrite 400 Tablet is a product of Torrent Pharmaceuticals Ltd

Composition: Pazopanib (400mg)

₹ 9770.63

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes
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All Details About Pazobrite 400 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Pazobrite 400 Tablet

Description:

Pazobrite 400 Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.

Pazobrite 400 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Diarrhea and high blood pressure are the most common side effects of this medicine. Doctor may advise for regular monitoring of your blood pressure while on treatment. Drink plenty of fluids to overcome diarrhea or consult with your doctor if it bothers you. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you experience fever, flu-like symptoms and shortness of breath.

Earlier taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pazobrite 400 Tablet is to be taken on an empty stomach.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Pazobrite

  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Pantingness
  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle or joint) pain
  • Chubbyigue
  • Alter in color of hair
  • Diarrhea

Warning & Precautions:

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pazobrite 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pazobrite 400 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Pazobrite 400 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Pazobrite 400 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Pazobrite 400 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver
CAUTION
Pazobrite 400 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Employ of Pazobrite 400 Tablet is not advised in patients with moderate to severe liver disease.

FAQs:

Is Pazobrite 400 Tablet a chemotherapy medicine?

Pazobrite 400 Tablet is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazobrite 400 Tablet works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

How should I take Pazobrite 400 Tablet?

Pazobrite 400 Tablet should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Can Pazobrite 400 Tablet be taken with food?

Pazobrite 400 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

How will I know if Pazobrite 400 Tablet is helping me?

The duration for which you have to continue taking Pazobrite 400 Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Are there any food restrictions while I’m taking Pazobrite 400 Tablet?

Affirmative, it is best to avoid grapefruit and grapefruit juice while on Pazobrite 400 Tablet, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

How long I have to take Pazobrite 400 Tablet?

The duration for which you have to continue taking Pazobrite 400 Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

What is the most important information I need to know about Pazobrite 400 Tablet?

Pazobrite 400 Tablet may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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