Oleanz Plus Tablet 10.0 tablets in 1 strip

Last Updated: April 13th, 2026

Oleanz Plus Tablet is a product of Sun Pharmaceutical Industries Ltd

Composition: Fluoxetine (20mg) + Olanzapine (5mg)

Pack of 10 tablet

₹ 135.94

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Oleanz Plus Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Oleanz Plus Tablet

Description:

Oleanz Plus Tablet is a prescription medicine used in the treatment of depression associated with bipolar disorder. It works by increasing the level of chemical messengers in the brain, which improves mood and physical symptoms of depression.

Oleanz Plus Tablet may be taken with or without food. Take it at the same time each day, as this helps maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and do not miss a dose. This medication must not be stopped suddenly without talking to your doctor, as it may worsen your symptoms.

Some common side effects of this medicine include dryness in the mouth, weight gain, and disturbance in attention. It may also cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these symptoms are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

Earlier taking Oleanz Plus Tablet, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, coughing, or allergy medication. You should avoid alcohol while taking Oleanz Plus Tablet, as it may worsen certain side effects.

Oleanz Plus Tablet can also lead to weight gain, eat a healthy, balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses:

Depression associated with Bipolar disorder
Bipolar depression

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oleanz Plus Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Oleanz Plus

Weight gain
Dryness in mouth
Edema (swelling)
Challengingy in paying attention
Chubbyigue
Increased appetite
Sedation
Sleepiness
Blurred vision

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Oleanz Plus Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Oleanz Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

UNSAFE

Oleanz Plus Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Oleanz Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Oleanz Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Oleanz Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is Oleanz Plus Tablet used for?

Oleanz Plus Tablet is used to treat depression in bipolar disorder (bipolar depression) and treatment-resistant depression (when other antidepressants haven’t worked). It combines an antidepressant (fluoxetine) and an antipsychotic (olanzapine) to help improve mood, sleep, appetite, and energy.

Can Oleanz Plus Tablet be used in children or elderly patients?

Oleanz Plus Tablet is not approved for children under 10 years of age and should be avoided in elderly people with dementia, as it increases the risk of death and stroke in such patients.

What are the serious side effects of Oleanz Plus Tablet I should know about?

During Oleanz Plus Tablet therapy, some serious side effects include suicidal thoughts (especially in younger people), severe allergic reactions (rash, swelling), high blood sugar or diabetes, unusual body movements (tardive dyskinesia), serotonin syndrome (confusion, sweating, fast heart rate), and seizures or fainting. Call your doctor right away if you notice any of these symptoms.

Does Oleanz Plus Tablet cause weight gain?

Affirmative. Weight gain and increased appetite are common side effects of Oleanz Plus Tablet. Regular weight checks are recommended during treatment.

Can I stop taking Oleanz Plus Tablet suddenly?

You should never stop taking Oleanz Plus Tablet suddenly. Doing so can lead to withdrawal symptoms like dizziness, mood swings, and flu-like feelings. Forever talk to your doctor before stopping.

What should I avoid while taking Oleanz Plus Tablet?

You should avoid consuming alcohol (increases drowsiness and blood pressure drops), operating vehicles or machinery if feeling sleepy, and other serotonin-boosting drugs unless approved by your doctor. Tell your doctor about all medications and supplements you take to avoid dangerous interactions.

Can Oleanz Plus Tablet affect my thinking or coordination?

Oleanz Plus Tablet may cause trouble thinking, drowsiness, or dizziness. Avoid driving or using heavy machinery until you know how it affects you.

Can Oleanz Plus Tablet affect my blood sugar or cholesterol levels?

Affirmative. Oleanz Plus Tablet can cause high blood sugar (even leading to diabetes) and high cholesterol or triglyceride levels. These should be monitored with blood tests during Oleanz Plus Tablet treatment.

How should I take Oleanz Plus Tablet?

Take Oleanz Plus Tablet exactly as prescribed, typically once daily in the evening with or without food. Swallow the tablets whole with water. Your doctor may start with a low dose and gradually increase it based on your response and tolerance.

How long does Oleanz Plus Tablet take to show results?

The exact time Oleanz Plus Tablet takes to show results is not known. However, some symptoms may improve within weeks, but full benefit often takes a few weeks to months of consistent use. Improvement in mood may take longer. You should continue taking it as prescribed even if you don't notice immediate improvements.

Can I drink alcohol while taking Oleanz Plus Tablet?

Alcohol should be avoided while taking Oleanz Plus Tablet, as it can worsen drowsiness and dizziness and may increase depression symptoms. Combining alcohol with Oleanz Plus Tablet can also impair judgment and increase the risk of dangerous behaviors.

What health monitoring is required during Oleanz Plus Tablet treatment?

Your doctor may advise regular health monitoring, including weight, blood pressure, blood sugar, and lipid profiles. Your doctor may also order periodic blood tests to check medication levels and monitor for metabolic changes or other side effects.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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