Mefron Plus Tablet

Last Updated: April 9th, 2026

Mefron Plus Tablet is a product of Ultra Chiron Pharmaceuticals Pvt Ltd

Composition: Mefenamic Acid (250mg) + Paracetamol (500mg)

₹ 32.81

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

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All Details About Mefron Plus Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Mefron Plus Tablet

Description:

Mefron Plus Tablet is a combination of two medicines. It is used in the treatment of fever. It is also useful for the treatment of mild to moderate pain of various conditions like headache, body ache, and toothache.

Mefron Plus Tablet is to be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, and heartburn. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Earlier taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefron Plus Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Mefron Plus

Vomiting
Diarrhea
Nausea
Indigestion
Loss of appetite
Heartburn

Warning & Precautions:

Alcohol

CAUTION

Alcohol should be used with caution while taking Mefron Plus Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Mefron Plus Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Mefron Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Mefron Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Mefron Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Employ of Mefron Plus Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Mefron Plus Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Mefron Plus Tablet is not recommended in patients with severe liver disease and active liver disease.

FAQs:

Is it safe to use Mefron Plus Tablet?

Affirmative, Mefron Plus Tablet is safe to use in most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem due to the medication.

Can Mefron Plus Tablet be stopped when the pain is relieved?

Mefron Plus Tablet is usually used for short term and can be discontinued when the pain is relieved. However, if advised by the doctor, it should be continued for the recommended time period.

Can the use of Mefron Plus Tablet cause nausea and vomiting?

Affirmative, the use of Mefron Plus Tablet can cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with the medicine. In the case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Communicate to the doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Mefron Plus Tablet cause dizziness?

Affirmative, the use of Mefron Plus Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Are there any specific contraindications associated with the use of Mefron Plus Tablet?

The use of Mefron Plus Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcer or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of liver or kidney disease.

Can I take Mefron Plus Tablet with vitamin B-complex?

Affirmative, Mefron Plus Tablet can be taken with Vitamin B-complex preparations. While Mefron Plus Tablet helps to relieve pain, Vitamin B-complex can help correct the vitamin deficiency that might be causing the underlying painful condition.

Can the use of Mefron Plus Tablet cause damage to kidneys?

Affirmative, the long-term use of Mefron Plus Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Employ of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Employ of painkillers is not recommended to patients with underlying kidney disease.

Is it safe to take a higher than the recommended dose of Mefron Plus Tablet?

No, taking a higher than the recommended dose of Mefron Plus Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage the kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the storage condition for Mefron Plus Tablet?

Retain this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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