Isot 20 Capsule 10.0 soft gelatin capsules in 1 strip

Last Updated: March 28th, 2026

Isot 20 Capsule is a product of Sanstuti Pharmaceuticals Pvt Ltd

Composition: Isotretinoin (20mg)

Pack of 10 soft

₹ 271.88

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Isot 20 Capsule

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Isot 20 Capsule

Description:

Isot 20 Capsule belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

Isot 20 Capsule should be used in the dose and duration as advised by your doctor. Take it with or without food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

Isot 20 Capsule may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Increaseitionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

Uses:

Treatment of Acne

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isot 20 Capsule may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Isot

Increased liver enzymes
Rash
Dry skin

Warning & Precautions:

Alcohol

CAUTION

Alcohol should be used with caution while taking Isot 20 Capsule.

Pregnancy

UNSAFE

Isot 20 Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Isot 20 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Isot 20 Capsule may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

CAUTION

Isot 20 Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Isot 20 Capsule is unsafe to use in patients with liver disease and should be avoided.

FAQs:

Is Isot 20 Capsule safe to use?

Isot 20 Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Isot 20 Capsule should not be used by pregnant women because it can cause severe birth defects.

Is Isot 20 Capsule a steroid?

No, Isot 20 Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the recommended tests during Isot 20 Capsule therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of Isot 20 Capsule permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Isot 20 Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Isot 20 Capsule.

Why is Isot 20 Capsule so dangerous during pregnancy?

If pregnancy occurs during treatment with Isot 20 Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.

Can Isot 20 Capsule cause cancer?

No, there are no reports of Isot 20 Capsule causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What are the long-term side effects of Isot 20 Capsule?

A normal course of treatment of Isot 20 Capsule is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does Isot 20 Capsule affect male fertility?

No, Isot 20 Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does Isot 20 Capsule damage your liver?

There may be a transient increase in liver enzymes with Isot 20 Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Isot 20 Capsule.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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