Tretosil 20mg Tablet 10.0 tablets in 1 strip

Last Updated: December 16th, 2025

Tretosil 20mg Tablet is a product of Stelon Biotech Private Limited

Composition: Isotretinoin (20mg)

Pack of 10 tablet

₹ 134.06

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Limited Stock

All Details About Tretosil 20mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Tretosil 20mg Tablet

Description:

Tretosil 20mg Tablet belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

Tretosil 20mg Tablet should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.

Tretosil 20mg Tablet may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Increaseitionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.

Uses:

Treatment of Acne

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tretosil 20mg Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Tretosil

Increased liver enzymes
Rash
Dry skin

Warning & Precautions:

Alcohol

CAUTION

Alcohol should be used with caution while taking Tretosil 20mg Tablet.

Pregnancy

UNSAFE

Tretosil 20mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Tretosil 20mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Tretosil 20mg Tablet may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Tretosil 20mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Tretosil 20mg Tablet in patients with liver disease.

FAQs:

Is Tretosil 20mg Tablet safe to use?

Tretosil 20mg Tablet should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Tretosil 20mg Tablet should not be used by pregnant women because it can cause severe birth defects.

Is Tretosil 20mg Tablet a steroid?

No, Tretosil 20mg Tablet is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the recommended tests during Tretosil 20mg Tablet therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of Tretosil 20mg Tablet permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Tretosil 20mg Tablet has shown that the symptoms in the patients with acne may continue to improve following treatment with Tretosil 20mg Tablet.

Why is Tretosil 20mg Tablet so dangerous during pregnancy?

If pregnancy occurs during treatment with Tretosil 20mg Tablet then, there is an extremely high risk that the baby may be born with severe birth defects.

Can Tretosil 20mg Tablet cause cancer?

No, there are no reports of Tretosil 20mg Tablet causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What are the long-term side effects of Tretosil 20mg Tablet?

A normal course of treatment of Tretosil 20mg Tablet is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does Tretosil 20mg Tablet affect male fertility?

No, Tretosil 20mg Tablet does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does Tretosil 20mg Tablet damage your liver?

There may be a transient increase in liver enzymes with Tretosil 20mg Tablet use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Tretosil 20mg Tablet.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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