Cafirate Injection

All Details About Cafirate Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Cafirate Injection

Description:

Cafirate Injection is a prescription medicine used in the treatment of apnea (a disorder in which breathing repeatedly stops and starts) of prematurity. It facilitates normal breathing and reduces interrupted breathing in premature newborns.

Cafirate Injection is given under the supervision of healthcare professionals. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.

Some common side effects of this medicine include mild delirium, insomnia, frequent urge to urinate, dehydration, tachycardia, and fever. Consult your doctor if these do not go away or persist for a longer duration. They may be able to suggest ways to prevent or reduce the side effects.

Uses:

Apnea of prematurity

Directions For Use:

Your doctor or nurse will give you this medicine. Compassionately do not self administer.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Cafirate

Delirium (acute confusional state)
Dehydration
Fever
Insomnia (difficulty in sleeping)
Frequent urge to urinate

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cafirate Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Cafirate Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Cafirate Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

NOT RELEVANT

Not relevant, as Cafirate Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Cafirate Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Cafirate Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is Cafirate Injection and why is it used in newborns?

Cafirate Injection is a medicine given to premature babies who have apnea of prematurity. This condition causes infants to stop breathing for short periods because their breathing system is not fully developed. Cafirate Injection helps stimulate the baby’s brain and lungs to improve breathing.

How does Cafirate Injection work in premature babies?

Cafirate Injection works by stimulating the central nervous system and the baby’s breathing center. It makes the brain more responsive to carbon dioxide and helps reduce episodes where the baby stops breathing. It also improves muscle tone and decreases fatigue of the diaphragm, the muscle that controls breathing.

Who should not receive Cafirate Injection?

Cafirate Injection should not be given to infants who are allergic or hypersensitive to caffeine, or any of the ingredients in the medicine. If a baby has shown any allergic reaction to caffeine in the past, this medicine should be avoided.

What serious risks are linked with Cafirate Injection in newborns?

One of the most serious risks linked to Cafirate Injection is necrotizing enterocolitis (a life-threatening bowel condition) that has been reported in premature babies during clinical studies. Because of this, babies receiving this medicine must be closely monitored for abdominal bloating, vomiting, bloody stools, or sudden changes in energy levels.

Can Cafirate Injection be used for long-term treatment?

No, Cafirate Injection is meant only for short-term treatment of apnea of prematurity, typically for ten to twelve days. Its safety and effectiveness for long-term use, or for other conditions such as sudden infant death syndrome (SIDS), have not been proven.

What precautions should doctors take before giving Cafirate Injection?

Earlier starting Cafirate Injection treatment, doctors should rule out other possible causes of apnea, such as infections, anemia, or lung disease. They may also need to check caffeine levels in babies who were previously given theophylline, or whose mothers consumed caffeine before delivery, since these can affect blood caffeine levels.

What should caregivers watch for while their baby is on Cafirate Injection?

While the baby is on Cafirate Injection treatment, parents or caregivers should immediately contact the doctor if the baby develops a swollen belly, vomiting, bloody stools, unusual sleepiness, or seems unwell. These may be signs of serious complications such as necrotizing enterocolitis.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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