Zyloric 300 Tablet 10.0 tablets in 1 strip

Last Updated: April 1st, 2026

Zyloric 300 Tablet is a product of Glaxo SmithKline Pharmaceuticals Ltd

Composition: Allopurinol (300mg)

Pack of 10 tablet

₹ 59.01

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Zyloric 300 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Zyloric 300 Tablet

Description:

Zyloric 300 Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body, and it forms crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.

Zyloric 300 Tablet should be taken with food. You should keep taking it as recommended by your doctor, even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.

Some of the common side effects of this medicine are diarrhea and increased liver enzymes. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction that needs urgent medical attention. Communicate to your doctor straight away if you get symptoms of liver disease, including nausea that does not stop, yellowing skin or eyes, or dark urine.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease, or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.

Uses:

Treatment of Gout

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyloric 300 Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Zyloric

Diarrhea
High serum glutamic oxaloacetic transaminase
High serum glutamic pyruvic transaminase
Increased alkaline phosphatase level in blood

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zyloric 300 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Zyloric 300 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Zyloric 300 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Zyloric 300 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zyloric 300 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zyloric 300 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is the best time of the day to take Zyloric 300 Tablet?

Zyloric 300 Tablet can be taken at any time of the day, but it should be taken at the same time each day so that you remember to take it. It is usually prescribed once daily and should be taken after meals. If the dose exceeds 300 mg or if your stomach is upset, you can take it in divided doses as advised by your doctor.

Why do I still get gout while taking Zyloric 300 Tablet?

If you have started taking Zyloric 300 Tablet, you may experience an increase in attacks of gout (severe pain, swelling, and redness). However, these attacks usually become shorter and less severe after several months of therapy. The possible reason for increased attacks could be the gradual breakdown of uric acid crystals, causing fluctuations in uric acid levels in the blood. To prevent such painful events, your doctor may advise taking colchicine with Zyloric 300 Tablet, as it can suppress the gouty attacks.

How long does it take for Zyloric 300 Tablet to lower uric acid levels?

It may take several months before you start feeling better or notice any significant reduction in attacks of gout (severe pain, swelling, and redness). Initially, after starting Zyloric 300 Tablet, you may experience gouty attacks. Continue taking Zyloric 300 Tablet even if you do not experience any considerable relief from the attacks. Do not stop taking Zyloric 300 Tablet without consulting your doctor. Your doctor will prescribe you another medicine along with Zyloric 300 Tablet to prevent the initial attacks. It may take a while for the body to completely get rid of all uric acid crystals.

What if I take alcohol while taking Zyloric 300 Tablet?

You should refrain from consuming alcohol while taking Zyloric 300 Tablet, as this could make your condition worse. Also, you should avoid all foods that are rich sources of protein, as it will help to prevent attacks of gout. Consult your doctor for a detailed list of food items that need to be avoided. It is also recommended that you drink at least 8 glasses of water or other fluids while taking Zyloric 300 Tablet unless your doctor has advised otherwise.

Does Zyloric 300 Tablet cause drowsiness?

Affirmative, Zyloric 300 Tablet may cause drowsiness in some people. It can even make you feel giddy (dizzy), or you may have problems with coordination. It would be best to avoid driving or operating machinery if you experience these side effects. However, if it is unavoidable, then extreme caution should be exercised while performing such tasks.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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