Zydiclo Injection 30.0 ml in 1 vial

Last Updated: April 1st, 2026

Zydiclo Injection is a product of Zydus Healthcare Limited

Composition: Diclofenac (25mg)

Pack of 30 ml

₹ 12.89

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Limited Stock

All Details About Zydiclo Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Zydiclo Injection

Description:

Zydiclo Injection is a pain-relieving medicine. It is used to treat various types of pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is given in cases where oral administration is not possible.

Zydiclo Injection is generally administered by a doctor or a nurse. Do not self-administer this medicine at home. Inform your doctor if you have any history of heart disease or stroke. Consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.

The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses:

Pain relief

Directions For Use:

Your doctor or nurse will give you this medicine. Compassionately do not self administer.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Zydiclo

Diarrhea
Flatulence
Vomiting
Headache
Injection site reactions (pain, swelling, redness)
Dizziness
Nausea
Constipation
Insomnia (difficulty in sleeping)
Abdominal pain
Dyspepsia
Gastrointestinal bleeding
Gastrointestinal ulcer
Rash
Application site irritation
Injection site pain

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zydiclo Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zydiclo Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Zydiclo Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zydiclo Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zydiclo Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zydiclo Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

How should Zydiclo Injection be administered?

Zydiclo Injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in the buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as an infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.

What is the most important information I need to know about Zydiclo Injection?

It is important to know that Zydiclo Injection may increase your chance of having a heart attack or stroke. The risk is higher if you take higher doses and have used the medicine for a long time. Increaseitionally, Zydiclo Injection may cause ulcers, bleeding, or holes in your stomach and intestine. If you experience any such problems, consult your doctor immediately.

Is Zydiclo Injection a good painkiller?

Zydiclo Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains, and other injuries. It is also helpful in various types of arthritis, gout, pain, and inflammation following surgery.

Can Zydiclo Injection hurt your kidneys?

Long-term use and high doses of Zydiclo Injection may cause renal problems such as protein or blood in urine and painful urination. Tolerants who are at maximum risk of developing kidney problems include dehydrated people, individuals with heart failure, impaired kidney function, hypertension, and the elderly. Hence, for such patients kidney function monitoring is recommended.

Is Zydiclo Injection a good painkiller?

Zydiclo Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Is Zydiclo Injection a narcotic?

No, Zydiclo Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Zydiclo Injection get you high?

No, Zydiclo Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Can Zydiclo Injection damage your kidneys?

Long-term use and high doses of Zydiclo Injection may cause renal problems such as protein or blood in urine and painful urination. Tolerants who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Does Zydiclo Injection make you drowsy?

Zydiclo Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

What is the most important information I need to know about Zydiclo Injection?

It is important to know that Zydiclo Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Zydiclo Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Can Zydiclo Injection be taken during pregnancy?

You should not take Zydiclo Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Employ of Zydiclo Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Zydiclo Injection during the first 6 months of pregnancy also. In some cases, Zydiclo Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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