Tubercin 450mg Capsule

Last Updated: December 16th, 2025

Tubercin 450mg Capsule is a product of Briskon Laboratories

Composition: Rifampicin (450mg)

₹ 51.56

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Restricted

All Details About Tubercin 450mg Capsule

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Tubercin 450mg Capsule

Description:

Tubercin 450mg Capsule is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. It may be used alone or in combination with other medicines to fight serious infections.

Tubercin 450mg Capsule may also be given to people who are carriers (people who are infected, yet do not show any signs and symptoms of infection). It should be taken on an empty stomach, at least 30 minutes before a meal or 2 hours after a meal. It should be taken in the dose and duration as advised by the doctor. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like low blood platelets, headache, dizziness, vomiting, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.

Earlier starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests for liver function tests while using this medicine.

Uses:

Tuberculosis (TB)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Tubercin 450mg Capsule is to be taken empty stomach.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Tubercin

Dizziness
Puzzleical reactions
Increased aspartate aminotransferase
Increased alanine aminotransferase
Increased bilirubin in the blood
Low blood platelets
Vomiting
Nausea
Fever
Abdominal pain
Skin rash
Hepatitis (viral infection of liver)
Headache
Chills

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Tubercin 450mg Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Tubercin 450mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Tubercin 450mg Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Tubercin 450mg Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.

Kidney

CAUTION

Tubercin 450mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Tubercin 450mg Capsule may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Tubercin 450mg Capsule in patients with liver disease. Please consult your doctor.

FAQs:

Is rifampin a penicillin/amoxicillin/sulfa drug?

No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs

Is rifampin bacteriostatic or bactericidal?

Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria

Is rifampin an inducer or inhibitor?

Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

What is R-cin 600 used for?

R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections

What is R-cinex/Macox plus/R-cinex 600?

R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid

Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?

Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?

No. Alters in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections

Does rifampin cause headaches?

Affirmative. Headache is a possible side effect of rifampin

Does rifampin change urine color/turn urine orange?

Affirmative. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful

Does rifampin cause liver damage?

Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

Disclaimer:

Getomeds primary intention is to ensure that its consumers get information that is reviewed by experts, accurate, and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all of your concerns about any disease or medication. Do not disregard or postpone seeking professional medical advice because of something you read on Getomeds. Our mission is to support, not replace, the doctor-patient relationship.