Trigli LS 1mg/500mg/7.5mg Tablet SR

Last Updated: October 7th, 2025

Trigli LS 1mg/500mg/7.5mg Tablet SR is a product of Ordain Health Care Global Pvt Ltd

Composition: Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (7.5mg)

₹ 29.91

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

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All Details About Trigli LS 1mg/500mg/7.5mg Tablet SR

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Trigli LS 1mg/500mg/7.5mg Tablet SR

Description:

Trigli LS /500mg/7.5mg Tablet SR is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.

Trigli LS /500mg/7.5mg Tablet SR should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, diarrhea, stomach pain, headache, bone fracture, and respiratory tract infection.

Earlier taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses:

Treatment of Type 2 diabetes mellitus

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trigli LS /500mg/7.5mg Tablet SR is to be taken with food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Trigli

Hypoglycemia (low blood glucose level)
Headache
Nausea
Diarrhea
Dizziness
Vomiting
Anemia (low number of red blood cells)
Weakness
Sinus infection

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Trigli LS /500mg/7.5mg Tablet SR.

Pregnancy

CONSULT YOUR DOCTOR

Trigli LS /500mg/7.5mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Trigli LS /500mg/7.5mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Trigli LS /500mg/7.5mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Trigli LS /500mg/7.5mg Tablet SR may be needed. Please consult your doctor.
Employ of Trigli LS /500mg/7.5mg Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Trigli LS /500mg/7.5mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Trigli LS /500mg/7.5mg Tablet SR may be needed. Please consult your doctor.
Employ of Trigli LS /500mg/7.5mg Tablet SR is not recommended in patients with severe liver disease.

FAQs:

Can I drink alcohol while taking Trigli LS /500mg/7.5mg Tablet SR?

No, it is not safe to drink alcohol while using Trigli LS /500mg/7.5mg Tablet SR. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.

What should I inform the doctor before taking Trigli LS /500mg/7.5mg Tablet SR?

Earlier taking Trigli LS /500mg/7.5mg Tablet SR inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.

Can the use of Trigli LS /500mg/7.5mg Tablet SR lead to Vitamin B12 deficiency?

Affirmative, the use of Trigli LS /500mg/7.5mg Tablet SR can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.

Can the use of Trigli LS /500mg/7.5mg Tablet SR cause hypoglycemia?

Affirmative, the use of Trigli LS /500mg/7.5mg Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Forever carry some sugary item like a candy or chocolate with you.

What are the instructions for the storage and disposal of Trigli LS /500mg/7.5mg Tablet SR?

Retain this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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