Toplift XL 75 Capsule PR 10.0 capsule pr in 1 strip

Last Updated: October 8th, 2025

Toplift XL 75 Capsule PR is a product of Ishjas Pharma Pvt Ltd

Composition: Venlafaxine (75mg)

Pack of 10 capsule

₹ 117.19

*Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Toplift XL 75 Capsule PR

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Toplift XL 75 Capsule PR

Description:

Toplift XL 75 Capsule PR is a medicine used to treat major depressive disorder and anxiety disorders. It helps improve mood, reduce nervousness, and improve overall well-being by restoring the balance of certain brain chemicals that affect mood and emotions.

Toplift XL 75 Capsule PR should be taken with food. Take this medicine at the same time each day to maintain a stable level in your blood. If you miss a dose, take it as soon as you remember. Do not skip doses, and complete the full course of treatment even if you feel better. Do not stop taking this medication abruptly, as it may worsen your symptoms.

Some common side effects of this medicine include nausea, insomnia (difficulty sleeping), constipation, increased sweating, and sexual dysfunction. However, these side effects are temporary and typically resolve on their own over time. Consult your doctor if these do not subside or bother you.

Toplift XL 75 Capsule PR may cause dizziness and drowsiness, so avoid driving or engaging in activities that require mental focus until you understand how this medicine affects you. Earlier taking Toplift XL 75 Capsule PR, inform your doctor if you have any kidney, heart, or liver conditions or a history of seizures (epilepsy or fits). Increaseitionally, notify your doctor if you experience any unusual mood or behavioral changes, worsening depression, or suicidal thoughts. Pregnant and breastfeeding women should consult before taking this medicine, as it may cause harmful effects on the developing baby.

Uses:

Directions For Use:

Employ it as advised by your doctor or check the label for directions before use. Toplift XL 75 Capsule PR is to be taken with food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Toplift XL

Nausea
Constipation
Increased sweating
Sexual dysfunction
Dizziness
Decreased appetite
Erectile dysfunction

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Toplift XL 75 Capsule PR.

Pregnancy

CONSULT YOUR DOCTOR

Toplift XL 75 Capsule PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Toplift XL 75 Capsule PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.

Driving

UNSAFE

Toplift XL 75 Capsule PR may cause side effects which could affect your ability to drive.
Toplift XL 75 Capsule PR may cause dizziness, confusion, and eyesight changes such as blurred vision, which may affect your ability to drive.

Kidney

CAUTION

Toplift XL 75 Capsule PR should be used with caution in patients with kidney disease. Dose adjustment of Toplift XL 75 Capsule PR may be needed. Please consult your doctor.

Liver

CAUTION

Toplift XL 75 Capsule PR should be used with caution in patients with liver disease. Dose adjustment of Toplift XL 75 Capsule PR may be needed. Please consult your doctor.

FAQs:

Can Toplift XL 75 Capsule PR cause sedation?

Affirmative. Toplift XL 75 Capsule PR can cause sedation. You should inform your doctor if you are taking any other sleep-inducing medicines before starting Toplift XL 75 Capsule PR.

Is Toplift XL 75 Capsule PR a psychotropic drug?

Affirmative. Toplift XL 75 Capsule PR is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Is Toplift XL 75 Capsule PR a narcotic?

No. Toplift XL 75 Capsule PR is not a narcotic drug. Narcotics are drugs with sleep-inducing properties, usually derivatives of opium, like heroin and morphine.

Can I take mirtazapine along with Toplift XL 75 Capsule PR?

No. There can be a serious side effect when mirtazapine is taken with Toplift XL 75 Capsule PR. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Can I take Toplift XL 75 Capsule PR with citalopram?

No. Citalopram and Toplift XL 75 Capsule PR both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

What is the relation between Toplift XL 75 Capsule PR and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Toplift XL 75 Capsule PR from the brain. Some studies have shown that Toplift XL 75 Capsule PR and its metabolite inhibit the p-glycoprotein.

Can Toplift XL 75 Capsule PR cause high blood pressure?

Toplift XL 75 Capsule PR treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Toplift XL 75 Capsule PR should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.

Can Toplift XL 75 Capsule PR cause constipation?

Affirmative. Toplift XL 75 Capsule PR is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.

Can Toplift XL 75 Capsule PR cause weight loss?

Affirmative. Toplift XL 75 Capsule PR is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Toplift XL 75 Capsule PR for several weeks. Please consult your doctor if it bothers you.

Can Toplift XL 75 Capsule PR cause addiction?

No. Toplift XL 75 Capsule PR does not have habit-forming potential.

Can I take Toplift XL 75 Capsule PR tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Can gabapentin be given along with Toplift XL 75 Capsule PR?

Affirmative, gabapentin can be given with Toplift XL 75 Capsule PR, but only with a consultation with a doctor. They both, when given together, cause an increase in drowsiness, sleepiness, and decreased concentration at work. Take it with caution.

Can fibromyalgia be treated with Toplift XL 75 Capsule PR?

Toplift XL 75 Capsule PR is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Toplift XL 75 Capsule PR in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Can nerve pain be treated with Toplift XL 75 Capsule PR?

Toplift XL 75 Capsule PR is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Why does Toplift XL 75 Capsule PR cause loss of appetite?

Toplift XL 75 Capsule PR is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

What are good alternatives to Toplift XL 75 Capsule PR, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence, talk to your doctor, and then you can have another drug. Do not stop Toplift XL 75 Capsule PR by yourself, it can lead to increased adverse effects.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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