Sugamet MC 500 Tablet SR 10.0 tablet sr in 1 strip

Last Updated: December 13th, 2025

Sugamet MC 500 Tablet SR is a product of Zydus Cadila

Composition: Metformin (500mg) + Methylcobalamin (750mcg)

Pack of 10 tablet

₹ 142.42

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Sugamet MC 500 Tablet SR

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Sugamet MC 500 Tablet SR

Description:

Sugamet MC 500 Tablet SR is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. It helps to maintain blood sugar levels and reduces the chances of developing serious complications of diabetes.

Sugamet MC 500 Tablet SR should be taken in the dose and duration as advised by your doctor. It is to be taken with food, preferably at the same time each day. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

It may cause side effects like taste change, nausea, diarrhea, stomach pain, and loss of appetite. However, these are temporary and usually subside on their own. Please consult your doctor in case these do not resolve or persist for a longer duration.

Earlier taking Sugamet MC 500 Tablet SR, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses:

Treatment of Type 2 diabetes mellitus

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sugamet MC 500 Tablet SR is to be taken with food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Sugamet MC

Nausea
Taste change
Loss of appetite
Diarrhea
Stomach pain

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sugamet MC 500 Tablet SR.

Pregnancy

CONSULT YOUR DOCTOR

Sugamet MC 500 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Sugamet MC 500 Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Sugamet MC 500 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Sugamet MC 500 Tablet SR may be needed. Please consult your doctor.
Employ of Sugamet MC 500 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Sugamet MC 500 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Sugamet MC 500 Tablet SR may be needed. Please consult your doctor.
Sugamet MC 500 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

FAQs:

What is Sugamet MC 500 Tablet SR used for?

Sugamet MC 500 Tablet SR is prescribed mainly for patients with diabetes who also have, or are at risk of, vitamin B12 deficiency-related nerve problems.

Who should not use Sugamet MC 500 Tablet SR?

Individuals should not take Sugamet MC 500 Tablet SR if they are allergic to metformin or methylcobalamin, have severe kidney disease, severe liver issues, or a history of lactic acidosis. It is contraindicated in people with acute heart failure, severe infection, or if you are dehydrated.

Are there any serious side effects of Sugamet MC 500 Tablet SR to watch for?

Although they are rare, serious side effects of Sugamet MC 500 Tablet SR include lactic acidosis (rapid breathing, severe drowsiness, muscle pain, and weakness), allergic reactions (rash, swelling, difficulty breathing), and severe loss of appetite. Perceivek medical attention immediately if these occur.

How long should I take Sugamet MC 500 Tablet SR, and when will I see results?

You should use Sugamet MC 500 Tablet SR as directed for the duration recommended by your doctor. Blood sugar control usually improves within days to weeks. Nerve health benefits may take longer. Long-term use is typical for ongoing diabetes management.

Why add Methylcobalamin to Metformin therapy?

Metformin (present in Sugamet MC 500 Tablet SR), when used for months to years, may lower vitamin B12 levels, leading to nerve damage or neuropathy. Increaseing methylcobalamin (present in Sugamet MC 500 Tablet SR) helps prevent or treat these complications and supports healthy nerve function.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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