Smilepill 21 Tablet 21.0 tablets in 1 strip

Last Updated: October 6th, 2025

Smilepill 21 Tablet is a product of Cafoli Lifecare Pvt. Ltd.

Composition: Ethinyl Estradiol (0.03mg) + Levonorgestrel (0.15mg)

Pack of 21 tablet

₹ 62.41

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Not Available

All Details About Smilepill 21 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Smilepill 21 Tablet

Description:

Smilepill 21 Tablet is a medicine used for contraception (to prevent pregnancy) and in the treatment of irregular periods. It helps to prevent the release of the egg and its fertilization by the sperm.

Smilepill 21 Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as per your doctor's advice. You will have to take the pill on day one of your menstrual cycle and continue taking it for a whole month. Once the pack gets over, start with a new one. If you experience vomiting within 4 hours of dose intake, take another tablet. In case you missed your dose and you are late by 12 hours in taking the missed dose, use a condom during intercourse for a period of 2 days.

Nausea, headache, constipation, fatigue, and breast pain are some commonly seen side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You might experience spotting or bleeding between menstrual periods or missed periods. Consult with your doctor if this occurs frequently or persists longer. Inform your doctor if you notice swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision, as it may be a sign of a blood clot.

Earlier taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of the uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Do not take the medicine if you are pregnant already or breastfeeding.

Uses:

Contraception

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Smilepill 21 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Smilepill

Headache
Breast pain
Nausea
Abdominal pain
Weight gain
Depression
Constipation
Chubbyigue

Warning & Precautions:

Alcohol

CAUTION

Caution is advised when consuming alcohol with Smilepill 21 Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Smilepill 21 Tablet is highly unsafe to use during pregnancy. Perceivek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Smilepill 21 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Smilepill 21 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Smilepill 21 Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Smilepill 21 Tablet in patients with liver disease. Please consult your doctor.

FAQs:

What is Smilepill 21 Tablet and what is it used for?

Smilepill 21 Tablet is a combined oral contraceptive medicine that contains two hormones estrogen and progesterone. It is used to prevent pregnancy.

What if I forget to take Smilepill 21 Tablet?

If you forget to take one tablet, take it as soon as you remember, even if it means taking two tablets at same time and then follow the usual dosing schedule. However, if you forget to take two or more doses, you may not be totally protected against pregnancy. In this case, start taking the tablet as soon as you remember and use a non-hormonal method of contraception such as condoms for at least next 7 days to prevent pregnancy. Frequent missing of doses may lead to unexpected vaginal bleeding or spotting (blood stain). Consult your doctor if this persists.

How and in what dose should I take Smilepill 21 Tablet?

Take this medicine as per the advice of your doctor. However, take it at the same time each day, to ensure consistent levels of medicine in your body.

Are there any specific contraindications associated with the use of Smilepill 21 Tablet?

The use of Smilepill 21 Tablet is not recommended to patients with known allergy to any of its components or excipients. It is not advised to be used by patients with a history of high blood pressure, heart disease, diabetes mellitus, migraine headache, liver disease or tumors, uterine bleeding, breast cancer, deep vein thrombosis and pulmonary embolism (blood clot).

Can Smilepill 21 Tablet be taken by a patient who smokes?

Smilepill 21 Tablet should not be taken by a person who smokes. Smoking increases the risk of serious side effects like death from heart attack, blood clots or stroke. The risk increases in patients who are obese or over 35 years of age and people who are heavy smokers. Inform your doctor if you smoke, before taking Smilepill 21 Tablet.

What if I miss my regular menstrual periods while taking Smilepill 21 Tablet?

If you miss your menstrual periods while taking Smilepill 21 Tablet, you may be pregnant. Some women may miss periods or have light periods while taking Smilepill 21 Tablet even if they are not pregnant. Contact your doctor if you think you are pregnant or have missed one or two periods. This may happen in case you are not taking Smilepill 21 Tablet at the same time every day.

Can Smilepill 21 Tablet cause bleeding or spotting between the regular menstrual periods?

Affirmative, Smilepill 21 Tablet can cause some unexpected bleeding or spotting, especially during the first three months. Do not stop taking Smilepill 21 Tablet because of this. This bleeding or spotting decreases with time. You may have unexpected bleeding if you do not take the pills regularly. Consult your doctor if the spotting continues for more than seven days or if the bleeding is heavy.

What if I vomit after taking Smilepill 21 Tablet?

If you vomit within 3-4 hours after taking Smilepill 21 Tablet tablet, then it is considered as a missed dose. So, you should take an another dose as soon as you feel well enough.

What are the common side effects of taking Smilepill 21 Tablet?

You may experience irregular vaginal bleeding while taking Smilepill 21 Tablet. Other common side effects include headache, nausea (feeling sick), acne, depression (sad mood), and breast pain. Most of them are temporary. If these persist, consult with your doctor.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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