Serene 25mg Tablet 10.0 tablets in 1 strip

Last Updated: December 15th, 2025

Serene 25mg Tablet is a product of RKG Pharma

Composition: Sertraline (25mg)

Pack of 10 tablet

₹ 20.63

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All Details About Serene 25mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Serene 25mg Tablet

Description:

Serene 25mg Tablet is a medicine that is used to treat major depressive disorder (MDD) and obsessive-compulsive disorder (OCD). It works by increasing the levels of serotonin, a natural chemical in the brain that plays an important role in mood, emotions, and behavior.

Serene 25mg Tablet should be taken exactly as prescribed by your doctor. It can be taken with or without food, but it is best to take it at the same time each day to help you remember. Treatment for depression and OCD often takes several weeks before you start to feel the full benefit, so it is important to keep taking the medicine regularly and not stop suddenly, even if you feel better.

Stopping the medicine too quickly may cause withdrawal symptoms or make your condition return. For the best results, combine the treatment with healthy habits such as regular sleep, exercise, and support from family, friends, or counseling if recommended.

Some common side effects of Serene 25mg Tablet include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty in sleeping), and diarrhea. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Earlier taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Inform your doctor about all the medicines you are taking to make sure you are safe.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Serene 25mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Serene

Delayed ejaculation
Erectile dysfunction
Indigestion
Insomnia (difficulty in sleeping)
Low sexual desire
Nausea
Tremors
Diarrhea
Increased sweating
Loss of appetite
Sleepiness
Taste change

Warning & Precautions:

Alcohol

CAUTION

Alcohol should be used with caution while taking Serene 25mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Serene 25mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Serene 25mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Serene 25mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Serene 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Serene 25mg Tablet is unsafe to use in patients with liver disease and should be avoided.

FAQs:

How long does it take for Serene 25mg Tablet to work?

You may start noticing an improvement in symptoms within 7 days of taking Serene 25mg Tablet. However, it may take longer to show a full response and will vary from person to person.

How long do I need to take Serene 25mg Tablet?

You should continue taking Serene 25mg Tablet as long as your doctor recommends taking it, which may be for several months. Doctors usually recommend the medicine for 6 months to a year after you no longer feel depressed. It is important to know that stopping the medication before the suggested time may cause depression to come back.

When is the best time to take Serene 25mg Tablet?

Serene 25mg Tablet is usually taken once a day and can be taken at any time of the day. It can be taken with or without food. Take it as per your convenience, but preferably at the same time each day. Some people who have sleep difficulty after taking Serene 25mg Tablet should take it in the morning. Whereas some take it at night to limit the side effects of nausea and vomiting.

Does Serene 25mg Tablet cause sleepiness?

Affirmative, Serene 25mg Tablet may commonly cause sleepiness. In case you feel dizzy, sleepy, or tired after taking Serene 25mg Tablet, you should avoid driving or using heavy machinery. This generally happens within the first few days and weeks after starting Serene 25mg Tablet, which may disappear after 2-3 months of use of Serene 25mg Tablet.

What does Serene 25mg Tablet do for anxiety?

Serene 25mg Tablet belongs to the selective serotonin reuptake inhibitor (SSRI) class of medicines. It increases the levels of serotonin, which is an important chemical and a neurotransmitter. This increase in serotonin levels can help to improve and regulate your mood, resulting in an improvement in the symptoms of anxiety.

Can I stop taking Serene 25mg Tablet if I am better now?

No, you should not stop taking Serene 25mg Tablet without consulting your doctor. This is because the sudden discontinuation of Serene 25mg Tablet may cause withdrawal symptoms. Hence, it is important to gradually reduce the dose with time (over several weeks or months).

What are the withdrawal symptoms of Serene 25mg Tablet?

The withdrawal symptoms of Serene 25mg Tablet include dizziness, nausea, numbness or tingling in the hands or feet, trouble sleeping, feeling agitated or anxious, headaches, and shaking. However, these symptoms are generally mild to moderate and disappear after 1-2 weeks of discontinuing Serene 25mg Tablet.

What are the symptoms of an overdose of Serene 25mg Tablet?

The symptoms of overdose of Serene 25mg Tablet include nausea, dizziness, fever, vomiting, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include fainting, delirium, heart problems, and changes in blood pressure. If you experience such symptoms, immediately contact your doctor or seek emergency medical services in a nearby hospital.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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