Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Sclerifuma 120 Capsule DR
Sclerifuma 120 Capsule DR is a medicine used in the treatment of multiple sclerosis (MS). It works by suppressing the inflammation and immune system that causes nerve damage in MS and helps reduce the worsening of the condition. However, it is not a cure for MS.
Sclerifuma 120 Capsule DR should be taken as advised by the doctor. You may take it with food to avoid an upset stomach. You may need to get regular blood and urine tests to monitor your blood cells, and kidney and liver function during treatment with this medicine. Take it regularly to get the most benefit from it. To help you remember, take it at the same time each day and do not stop taking until you have completed your dose.
Some common side effects of this medicine include flushing, abdominal pain, diarrhea, nausea, vomiting, indigestion, gastritis, increased liver enzymes, and rash. If you experience any of these side effects that do not go away or get worse, let your doctor know. They may be able to suggest ways to prejudice or prevent them.
Earlier using this medicine, tell your doctor if you have low white blood cell counts or an infection. Let your doctor also know of all the medical conditions and about the medicines you are taking to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctor first before using this medicine as it may cause harmful effects to the developing baby.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sclerifuma 120 Capsule DR should be taken with or after food.
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Ordinary side effects of Sclerifuma
Vomiting
Diarrhea
Nausea
Abdominal pain
Indigestion
Stomach inflammation
Increased liver enzymes
Rash
Flushing (sense of warmth in the face, ears, neck and trunk)
Warning & Precautions:
Alcohol
CAUTION
Alcohol should be used with caution while taking Sclerifuma 120 Capsule DR.
Pregnancy
UNSAFE
Sclerifuma 120 Capsule DR is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Sclerifuma 120 Capsule DR during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Sclerifuma 120 Capsule DR does not usually affect your ability to drive.
Kidney
CAUTION
Sclerifuma 120 Capsule DR should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Sclerifuma 120 Capsule DR should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
FAQs:
What is Sclerifuma 120 Capsule DR used for?
Sclerifuma 120 Capsule DR is used to treat relapsing‑remitting multiple sclerosis (MS) in adults and children aged 13 years and older. It helps reduce the frequency of MS relapses and may slow disease progression.
Who should not take Sclerifuma 120 Capsule DR?
Individuals should not take Sclerifuma 120 Capsule DR if they are allergic to dimethyl fumarate or any ingredient in the medicine, or if they have suspected or confirmed progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection.
What is PML, and how does Sclerifuma 120 Capsule DR relate to it?
Progressive multifocal leukoencephalopathy (PML) is a rare, potentially fatal brain infection caused by a virus. Cases have been reported in patients taking Sclerifuma 120 Capsule DR, especially those with low white blood cell counts (lymphopenia). Your doctor will monitor your blood counts regularly to reduce this risk.
Can Sclerifuma 120 Capsule DR cause low white blood cell counts?
Affirmative. Sclerifuma 120 Capsule DR can lower lymphocyte counts, which may increase infection risk. Your doctor will check your blood before starting treatment and every 3 months during therapy. Treatment may be stopped if your counts drop too low for more than 6 months.
What serious side effects of Sclerifuma 120 Capsule DR require immediate medical attention?
Earnest side effects of Sclerifuma 120 Capsule DR include PML (new weakness, vision changes, confusion, personality changes), severe allergic reactions (swelling, breathing trouble, rash), or symptoms of liver problems (yellowing skin or eyes, severe stomach pain).
Are there any kidney or liver concerns with Sclerifuma 120 Capsule DR?
Affirmative. Sclerifuma 120 Capsule DR may cause kidney changes and liver enzyme elevations. Your doctor will check your kidney and liver function before you start and periodically during treatment. Employ with caution if you have severe kidney or liver disease.
Can I get infections like shingles while taking Sclerifuma 120 Capsule DR?
Affirmative. Herpes zoster (shingles) infections have been reported while taking Sclerifuma 120 Capsule DR. Tell your doctor immediately if you develop painful blisters, rash, burning skin, or flu‑like symptoms, especially if you have low white blood cell counts.
Can Sclerifuma 120 Capsule DR cause flushing or stomach problems?
Affirmative. Flushing (redness, warmth) and gastrointestinal side effects (diarrhea, nausea, stomach pain) are very common, especially in the first month of Sclerifuma 120 Capsule DR treatment. Taking the medicine with food can help reduce these effects. Your doctor may temporarily lower the dose.
What is Fanconi syndrome, and can Sclerifuma 120 Capsule DR cause it?
Fanconi syndrome is a rare kidney disorder that has been reported with fumarate‑containing medicines such as Sclerifuma 120 Capsule DR. Symptoms include increased urination, thirst, muscle weakness, or bone pain. Contact your doctor if you notice these signs, so testing can be done.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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