Sayana Press 104mg Injection 0.65 ml in 1 vial

Last Updated: December 16th, 2025

Sayana Press 104mg Injection is a product of Pfizer Ltd

Composition: Medroxyprogesterone acetate (104mg)

Pack of 1 ml

₹ 515.63

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All Details About Sayana Press 104mg Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Sayana Press 104mg Injection

Description:

Expressana Press 104mg Injection is used for contraception (preventing pregnancy). It helps to prevent development and release of egg from the ovaries during menstrual cycle thus prevents pregnancy.

Expressana Press 104mg Injection is administered only by or under the supervision of doctor. It should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You should take this injection for as long as it is prescribed for you.

The most common side effects of this medicine include headache, dizziness, abdominal pain, nervousness, weight gain, and breast tenderness. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. It may also cause irregular menstrual cycle, spotting or your menstrual bleeds to stop altogether. Inform your doctor if you get heavy or prolonged bleeding.

Earlier taking this medicine, you must let your doctor know if you ever had any problems like history of blood clots, stroke, heart attack, liver, or bleeding problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must not take it if you are pregnant.

Uses:

Directions For Use:

Your doctor or nurse will give you this medicine. Compassionately do not self administer.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Expressana Press

Weight gain
Breast tenderness
Headache
Abdominal pain
Weakness
Dizziness
Irregular menstrual cycle
Tenseness

Warning & Precautions:

Alcohol

CAUTION

Caution is advised when consuming alcohol with Expressana Press 104mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Expressana Press 104mg Injection is highly unsafe to use during pregnancy. Perceivek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Expressana Press 104mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Nonhormonal contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum

Driving

UNSAFE

Expressana Press 104mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Expressana Press 104mg Injection in patients with kidney disease. Please consult your doctor.

Liver

UNSAFE

Expressana Press 104mg Injection is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

FAQs:

What is Expressana Press 104mg Injection used for?

Expressana Press 104mg Injection is a birth control method for women. It is made up of a hormone similar to progesterone, which is naturally produced in the body. It helps to prevent the development and release of egg from the ovaries during menstrual cycle thus prevents pregnancy.

When and how to take Expressana Press 104mg Injection ?

The first dose is usually given within 5 days of starting of your period. It is given as an injection into the muscle of the arm or buttocks, either by a doctor or nurse. A single dose of this injection is effective for 12 weeks. Therefore, after every 12 weeks you need to take this injection to avoid pregnancy.

Does Expressana Press 104mg Injection provide 100% protection from pregnancy?

No, Expressana Press 104mg Injection is only 97% effective, which means 3 out of 100 women using Expressana Press 104mg Injection may get pregnant. However, if you are taking every dose on time then the medicine can be more than 99% effective.

Can I become pregnant after I stop using Expressana Press 104mg Injection?

Affirmative, your fertility returns to normal after a few months of stopping Expressana Press 104mg Injection (on average three months, but it may take up to 1 year). However, if you are planning to get pregnant soon, avoid taking Expressana Press 104mg Injection unless otherwise prescribed by your doctor.

What are the side effects of using Expressana Press 104mg Injection?

The side effects associated with Expressana Press 104mg Injection include irregular menstrual periods or no periods at all, weight gain, headache, stomach pain, dizziness, acne and breast tenderness. Do not worry, as most of these side effects are temporary. However, if these side effects persist, consult your doctor.

When does Expressana Press 104mg Injection start working?

Expressana Press 104mg Injection starts working immediately if given within the first 5 days of beginning of your periods. But, if you receive the dose at another time of your menstrual cycle then it may take about 7 to 10 days to show effectiveness. Therefore, during these days, you must use some other contraceptive method such as condoms to avoid pregnancy.

What are the advantages of using Expressana Press 104mg Injection?

Expressana Press 104mg Injection is almost 100% effective and has many advantages. A single dose works for at least 12 weeks. During that time, you do not need to take daily oral contraceptive pills. It does not interfere with sexual intercourse. Moreover, it also reduces the risk of endometrial cancer (cancer of the lining of the uterus) by 80%. It may also be helpful in relieving painful periods.

What if I am late for my injection?

Expressana Press 104mg Injection injections should be given every 12 weeks. If you wait longer than 13 weeks between injections, you may need to take a pregnancy test before your next injection. You should opt for other methods of contraception, like condoms, for 14 days after having the late injection.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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