Samston Tablet 4.0 tablets in 1 strip

Last Updated: December 16th, 2025

Samston Tablet is a product of Efpia Medicine Private Limited

Composition: Tolvaptan (15mg)

Pack of 4 tablet

₹ 628.13

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Limited Stock

All Details About Samston Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Samston Tablet

Description:

Samston Tablet is a medicine used in the treatment of low levels of sodium in the blood. It treats low levels of sodium in the blood, which can result from conditions such as heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone (SIADH).

Samston Tablet can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.

Using this medicine may cause few common side effects such as frequent urge to urinate, nocturia (increased urge to urinate during the night), dryness in mouth, increased thirst, nausea, increased blood creatinine, hyperkalemia, and constipation. Let your doctor know if any of these side effects do not go away with time or get worse. Earlier using this medicine, inform your doctor if you have any problems with your kidneys or liver. While on this medicine, your doctor will closely monitor the sodium levels in your blood. You should also tell your doctor all the other medications you are taking.

Uses:

Treatment of Low levels of sodium in the blood
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samston Tablet may be taken with or without food, but it is better to take it at a fixed time.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Samston

Frequent urge to urinate
Nocturia (increased urge to urinate during the night)
Dryness in mouth
Increased thirst
Constipation
Nausea
Increased creatinine level in blood
Increased potassium level in blood

Warning & Precautions:

Alcohol

CAUTION

Caution is advised when consuming alcohol with Samston Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Samston Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Samston Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Samston Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Samston Tablet is safe to use in patients with kidney disease. No dose adjustment of Samston Tablet is recommended.
However, the use of Samston Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Samston Tablet should be used with caution in patients with liver disease. Dose adjustment of Samston Tablet may be needed. Please consult your doctor.
Employ of Samston Tablet is not recommended in patients with severe liver disease.

FAQs:

What is the most important information I need to be aware of while taking Samston Tablet?

Samston Tablet may cause the level of sodium in your blood to increase too quickly. This quick increase in sodium levels [osmotic demyelination syndrome (ODS)] may cause serious nerve damage, which can further cause coma and even death. The symptoms of ODS could be trouble in speaking, trouble in swallowing or a feeling of food or liquid getting stuck while swallowing, drowsiness, confusion, mood changes, fits, trouble controlling body movement (involuntary movement) and weakness in muscles of the arms and legs.

For how long do I need to take Samston Tablet?

Samston Tablet is used for correction of sodium levels in blood. Though the dose and duration are prescribed by the doctor, Samston Tablet should not be taken for more than 30 days. Once the sodium levels return to normal, it can be stopped after talking to the doctor.

Does Samston Tablet affect the sugar levels in blood?

Affirmative, Samston Tablet may increase the blood sugar levels. Therefore, patients with diabetes mellitus need to be extra careful while taking Samston Tablet and should keep a check on blood sugar levels regularly.

Who should not take Samston Tablet?

You should not take Samston Tablet if you have low sodium levels, cannot replace fluids by drinking or if you cannot tell when you are thirsty, dizzy or feeling faint or if your kidneys are not working properly because of excessive loss of fluids. You should also avoid Samston Tablet if your body is not able to make urine, you are allergic to Samston Tablet or if you are on certain medicines which interfere with the working of Samston Tablet.

Can I have grapefruit juice while taking Samston Tablet?

No, you should not take grapefruit or grapefruit juice while on Samston Tablet. The reason being, grapefruit or grapefruit juice may increase the levels of Samston Tablet in your blood and your sodium levels may rise too quickly.

What will happen if I take excess of Samston Tablet?

You may need urgent medical attention. Call your doctor or seek emergency service at a nearby hospital. Symptoms of taking too much Tolvaptan may include thirst, dry and flaky skin, sunken eyes, rapid heartbeat, rapid and shallow breathing, very low blood pressure, passing more urine than normal and fainting.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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