All Details About Ronapreve 120mg Injection Combi Pack
Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Ronapreve 120mg Injection Combi Pack
Ronapreve 120mg Injection Combi Pack contains two monoclonal antibodies used together for the emergency treatment of mild to moderate COVID-19 in adults and children aged 12 years and above and over 40 kg in weight. It is most effective if taken after an early laboratory diagnosis (within 7 to 10 days).
This monoclonal antibody cocktail received emergency use approval from the Central Drug Standard Control Organization (CDSCO) on May 3rd, 2021. Apart from India, it has been approved for use in the Joind States, Switzerland, Germany, Italy, France, and several other countries.
Ronapreve 120mg Injection Combi Pack should be given either into a vein (intravenously) or below the skin (subcutaneously) by a trained healthcare professional, preferably in a hospital setup. This is because the use of monoclonal antibodies may cause some side effects that may need immediate medical attention, such as severe allergic reactions (anaphylaxis). Tolerants should be monitored during and at least 1 hour after the injection.
The most common side effects of this monoclonal antibody therapy are injection site reactions, fever, flushing, shortness of breath, chest tightness, nausea, and vomiting. If you experience any of these side effects, let your doctor know immediately.
Earlier receiving this medicine, let your doctor know if you have any pre-existing medical conditions. Let the doctor know about your other medications if any, as they may affect or get affected by this COVID-19 drug. This medicine may be given to pregnant or breastfeeding women after considering its benefits against the risk to the baby or the mother.
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Uses:
Treatment of Mild to moderate Coronavirus disease (COVID-19)
Directions For Use:
Ordinary side effects of Ronapreve
Injection site reactions (pain, swelling, redness)
Fever
Flushing (sense of warmth in the face, ears, neck and trunk)
Pantingness
Chest tightness
Nausea
Vomiting
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Warning & Precautions:
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ronapreve 120mg Injection Combi Pack. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Ronapreve 120mg Injection Combi Pack during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ronapreve 120mg Injection Combi Pack during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Ronapreve 120mg Injection Combi Pack does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Ronapreve 120mg Injection Combi Pack is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ronapreve 120mg Injection Combi Pack may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Ronapreve 120mg Injection Combi Pack in patients with liver disease. Please consult your doctor.
FAQs:
Q. What are monoclonal antibodies? How are they relevant to Ronapreve 120mg Injection Combi Pack?
Monoclonal antibodies are specific proteins that mimic the immune system’s ability to fight against harmful microorganisms like viruses. Casirivimab and Imdevimab, the monoclonal antibodies present in Ronapreve 120mg Injection Combi Pack, help protect against the deadly SARS-CoV-2, the virus that causes COVID-19.
Q. What is a monoclonal antibody cocktail?
A monoclonal antibody cocktail is a combination of monoclonal antibodies that are available separately, but are mixed together for use as a cocktail, hence the name.
Q. How are monoclonal antibodies helpful in treating COVID-19?
SARS-CoV-2, the virus that causes COVID-19, has a spike protein on its surface that helps the virus to attach and enter the hu n body. Monoclonal antibodies are engineered to mimic this attachment with SARS-CoV-2, thereby preventing disease progression. Monoclonal antibody therapy may help in treating mild symptoms at the initial stages.
Q. When should monoclonal antibody therapy for COVID-19 be taken?
Monoclonal antibody therapy for COVID-19 should be taken after the early diagnosis of COVID-19 in patients aged 12 years or older with a bodyweight of at least 40 kg. It may also be taken by people who are at a high risk of developing a severe infection, such as those aged 60 years or above, who have comorbidities such as diabetes or hypertension, and those who are immunocompromised.
Q. Who should not take monoclonal antibodies for COVID-19?
Monoclonal antibodies for COVID-19 should not be taken by those who are hospitalized or need oxygen therapy. Increaseitionally, it should not be taken by those under oxygen treatment due to pre-existing comorbidities that may not be associated with COVID-19. Those who are allergic to any of the two medicines in Ronapreve 120mg Injection Combi Pack or any of the other ingredients of the kit should also avoid taking this combination of monoclonal antibodies.
Q. Who is at high risk of developing severe COVID-19?
People aged above 60 years, who are obese, have comorbid conditions related to lungs, kidneys (like dialysis patients), liver, or those who have a weak immunity (like cancer patients) are at high risk of developing severe COVID-19.
Q. How is Ronapreve 120mg Injection Combi Pack used?
Ronapreve 120mg Injection Combi Pack is given as an injection into a vein (intravenously) or below the skin (subcutaneously), by a healthcare professional, in a hospital to treat mild to moderate symptoms of COVID-19. It should never be injected into a muscle (intramuscularly).
Q. I have high blood pressure and diabetes. Can I take Ronapreve 120mg Injection Combi Pack?
Affirmative, Ronapreve 120mg Injection Combi Pack can be taken by patients with high blood pressure or diabetes, if prescribed. As per the available data, the benefits of using monoclonal antibody therapy are more significant than the potential risks.
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