Pyzina 1000 Tablet

Last Updated: March 17th, 2026

Pyzina 1000 Tablet is a product of Lupin Ltd

Composition: Pyrazinamide (1000mg)

₹ 112.35

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

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All Details About Pyzina 1000 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Pyzina 1000 Tablet

Description:

Pyzina 1000 Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

Pyzina 1000 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses:

Tuberculosis (TB)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyzina 1000 Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Pyzina

Jaundice
Hepatitis (viral infection of liver)
Increased liver enzymes
Joint pain

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pyzina 1000 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pyzina 1000 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Pyzina 1000 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Pyzina 1000 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Pyzina 1000 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Kidney function tests are advised before you start taking this medicine.

Liver

UNSAFE

Pyzina 1000 Tablet is unsafe to use in patients with liver disease and should be avoided.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

FAQs:

What is Pyzina 1000 Tablet and what is it used for?

Pyzina 1000 Tablet is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

Is Pyzina 1000 Tablet bactericidal?

Pyzina 1000 Tablet is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

How does Pyzina 1000 Tablet work/treat tuberculosis?

Pyzina 1000 Tablet kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Pyzina 1000 Tablet is not known

How does Pyzina 1000 Tablet cause hyperuricemia and gout?

Following oral intake of Pyzina 1000 Tablet, it gets converted in the body to pyrazinoic acid (active chemical form of Pyzina 1000 Tablet). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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