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Ugesic 10mg Tablet (Rs.90)
Composition: Piroxicam (10mg)
All Details About Pirox 10mg Capsule
Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Pirox 10mg Capsule
Description:
Pirox 10mg Capsule is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.Pirox 10mg Capsule should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Earlier using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Uses:
Directions For Use:
Ordinary side effects of Pirox
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themWarning & Precautions:
Alcohol
UNSAFE
It is unsafe to consume alcohol with Pirox 10mg Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Pirox 10mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pirox 10mg Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Pirox 10mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pirox 10mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Pirox 10mg Capsule may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Pirox 10mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Pirox 10mg Capsule may be needed. Please consult your doctor.
FAQs:
Q. What is the difference between Pirox 10mg Capsule and diclofenac?
Both Pirox 10mg Capsule and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pirox 10mg Capsule.
Q. What is the difference between Pirox 10mg Capsule and naproxen?
Both Pirox 10mg Capsule and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pirox 10mg Capsule.
Q. What is the difference between Pirox 10mg Capsule and meloxicam?
Both Pirox 10mg Capsule and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pirox 10mg Capsule.
Q. What is the difference between Pirox 10mg Capsule and ketoprofen?
Both Pirox 10mg Capsule and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pirox 10mg Capsule. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Pirox 10mg Capsule and tramadol?
Pirox 10mg Capsule is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Pirox 10mg Capsule and nimesulide?
Both Pirox 10mg Capsule and nimesulide are pain killers. However, Pirox 10mg Capsule is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Pirox 10mg Capsule be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pirox 10mg Capsule or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pirox 10mg Capsule.
Q. Are Pirox 10mg Capsule and aspirin same?
No. Pirox 10mg Capsule and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Pirox 10mg Capsule be used along with dexamethasone?
No. Pirox 10mg Capsule should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Pirox 10mg Capsule be used with methocarbamol?
Affirmative. Methocarbamol can be used with Pirox 10mg Capsule as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Pirox 10mg Capsule be used along with paracetamol?
Affirmative. Paracetamol can be used with Pirox 10mg Capsule as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Pirox 10mg Capsule a NSAID?
Affirmative. Pirox 10mg Capsule is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Pirox 10mg Capsule a sulfa drug?
Pirox 10mg Capsule is a sulphur containing compound. Pirox 10mg Capsule can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Pirox 10mg Capsule a blood thinner?
No. Pirox 10mg Capsule is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Pirox 10mg Capsule a muscle relaxant?
No. Pirox 10mg Capsule is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Pirox 10mg Capsule a narcotic?
No. Pirox 10mg Capsule is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Pirox 10mg Capsule be used in hypertension?
No. Pirox 10mg Capsule is not a medication to control hypertension. It is important to note that Pirox 10mg Capsule decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pirox 10mg Capsule.
Q. Can Pirox 10mg Capsule be used along with Losartan?
No. Pirox 10mg Capsule should not be combined with Losartan. It is important to note that Pirox 10mg Capsule decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirox 10mg Capsule.
Q. Can Pirox 10mg Capsule be used with Lisinopril?
No. Pirox 10mg Capsule should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirox 10mg Capsule.
Q. Can Pirox 10mg Capsule be used with calcium channel blocker?
Affirmative. Pirox 10mg Capsule can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Pirox 10mg Capsule be used with Tizanidine?
Affirmative, Pirox 10mg Capsule can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Pirox 10mg Capsule?
Affirmative. Pirox 10mg Capsule can be combined with beta-cyclodextrin. Research has shown that combining Pirox 10mg Capsule with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Pirox 10mg Capsule?
Affirmative. There are alternatives to Pirox 10mg Capsule. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Pirox 10mg Capsule?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Pirox 10mg Capsule be used in the treatment of allergy?
No. Pirox 10mg Capsule is not a drug to treat allergy. It is a pain killer.
Q. How long does Pirox 10mg Capsule work?
Pirox 10mg Capsule is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Pirox 10mg Capsule?
No. Pirox 10mg Capsule is not known to cause high. It is a non-narcotic painkiller.
Q. Can Pirox 10mg Capsule be used to treat menstrual cramp?
Pirox 10mg Capsule is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Pirox 10mg Capsule for a migraine?
Pirox 10mg Capsule is not approved for the treatment of migraine. Research studies have shown that Pirox 10mg Capsule is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Pirox 10mg Capsule effective in back pain management?
Affirmative. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pirox 10mg Capsule as the cause of back pain can be different for different person.
Q. Is Pirox 10mg Capsule affective in gout management?
Affirmative. Pirox 10mg Capsule can be given for the treatment of acute gout. Research studies have shown Pirox 10mg Capsule to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Pirox 10mg Capsule?
Affirmative. You can donate blood when on Pirox 10mg Capsule. Do inform your doctor before donating blood.
Q. Can I use Pirox 10mg Capsule if I am a diabetic?
Pirox 10mg Capsule in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirox 10mg Capsule so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Pirox 10mg Capsule if I have a deranged renal function?
No. Pirox 10mg Capsule should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Pirox 10mg Capsule lead to skin reactions?
Affirmative. Pirox 10mg Capsule is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Pirox 10mg Capsule if I am pregnant?
No. Pirox 10mg Capsule should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Pirox 10mg Capsule if I have peptic ulcer disease?
No. Pirox 10mg Capsule is contraindicated in cases of active peptic ulcer disease. Pirox 10mg Capsule is known to cause gastric ulceration and bleeding.
Q. Can I use Pirox 10mg Capsule if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Pirox 10mg Capsule lead to difficulty in conception?
Affirmative. Pirox 10mg Capsule can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Pirox 10mg Capsule be used with diuretics?
No. Pirox 10mg Capsule should not be used with diuretics. Pirox 10mg Capsule reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Pirox 10mg Capsule be used with lithium?
No. Pirox 10mg Capsule should not be used with lithium. Pirox 10mg Capsule leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Pirox 10mg Capsule be used with warfarin?
No. Pirox 10mg Capsule should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Pirox 10mg Capsule?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirox 10mg Capsule?
Tolerants who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Pirox 10mg Capsule?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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