Perindosyl AM 5mg/4mg Tablet 10.0 tablets in 1 strip

Last Updated: December 12th, 2025

Perindosyl AM 5mg/4mg Tablet is a product of Elder Pharmaceuticals Ltd

Composition: Amlodipine (5mg) + Perindopril erbumine (4mg)

Pack of 10 tablet

₹ 140.63

*Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Limited Stock

All Details About Perindosyl AM 5mg/4mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Perindosyl AM 5mg/4mg Tablet

Description:

Perindosyl AM 5mg/4mg Tablet is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke.

You can take Perindosyl AM 5mg/4mg Tablet at any time of day, on empty stomach, but it is best to take it at the same time each day. Retain taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Retaining active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

It may cause side effects like ankle swelling, headache, cough, weakness, shortness of breath, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.

Earlier taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

Uses:

Hypertension (high blood pressure)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perindosyl AM 5mg/4mg Tablet is to be taken empty stomach.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Perindosyl AM

Ankle swelling
Headache
Fatiguedness
Palpitations
Increased potassium level in blood
Sleepiness
Cough
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Decreased blood pressure
Agitated stomach
Erectile dysfunction
Eczema

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Perindosyl AM 5mg/4mg Tablet.

Pregnancy

UNSAFE

Perindosyl AM 5mg/4mg Tablet is highly unsafe to use during pregnancy. Perceivek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Perindosyl AM 5mg/4mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Perindosyl AM 5mg/4mg Tablet may cause side effects which could affect your ability to drive.
Perindosyl AM 5mg/4mg Tablet usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.

Kidney

UNSAFE

Perindosyl AM 5mg/4mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Caution should be advised in patients with renal impairment.

Liver

UNSAFE

Perindosyl AM 5mg/4mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

FAQs:

What is Perindosyl AM 5mg/4mg Tablet used for?

Perindosyl AM 5mg/4mg Tablet is used to treat high blood pressure (hypertension) when a single blood pressure–lowering medication is not effective. It helps relax blood vessels, improve blood flow, and reduce strain on the heart, lowering the risk of heart attack and stroke.

Who should not take Perindosyl AM 5mg/4mg Tablet?

Individuals should not take Perindosyl AM 5mg/4mg Tablet if they are allergic to amlodipine, perindopril, or any ACE inhibitors, or have ever had swelling of the face or throat (angioedema). It is also not suitable for people with very low blood pressure, severe heart failure after a heart attack, or serious narrowing of the heart valves.

Can Perindosyl AM 5mg/4mg Tablet cause serious allergic reactions?

Although rare, Perindosyl AM 5mg/4mg Tablet can cause a serious allergic reaction called angioedema, which may lead to swelling of the face, lips, tongue, or throat. This can block breathing and may be life-threatening. If you notice swelling or difficulty breathing, seek emergency medical help immediately.

What are the serious side effects of Perindosyl AM 5mg/4mg Tablet?

Some serious side effects of Perindosyl AM 5mg/4mg Tablet include severe dizziness or fainting from low blood pressure, chest pain, irregular heartbeat, kidney problems, yellowing of the skin or eyes (liver issues), or persistent cough. Any sudden swelling of the face or severe abdominal pain should also be reported to a doctor without delay.

Does Perindosyl AM 5mg/4mg Tablet affect the kidneys?

Affirmative, Perindosyl AM 5mg/4mg Tablet can affect kidney function, especially in people with pre-existing kidney problems, diabetes, or those taking diuretics. Your doctor may order regular blood tests to monitor kidney health and potassium levels while you are on this treatment.

Can Perindosyl AM 5mg/4mg Tablet cause low blood pressure?

Affirmative, Perindosyl AM 5mg/4mg Tablet can sometimes lower blood pressure too much, especially in patients who are dehydrated, on a low-salt diet, or taking water pills (diuretics). Symptoms of low blood pressure may include dizziness, fainting, or blurred vision. If you feel very weak or lightheaded, you should lie down and contact your doctor.

Does Perindosyl AM 5mg/4mg Tablet affect people with liver problems?

Affirmative, people with liver disease should take Perindosyl AM 5mg/4mg Tablet with caution, as amlodipine present in Perindosyl AM 5mg/4mg Tablet is cleared slowly from the body in such cases. Your doctor may closely monitor liver function and adjust your treatment if needed.

Can Perindosyl AM 5mg/4mg Tablet cause high potassium levels?

Affirmative, Perindosyl AM 5mg/4mg Tablet can increase potassium in the blood, especially if you already have kidney problems or take other medicines that raise blood potassium levels. High potassium can cause dangerous heart rhythm changes. Regular blood tests help ensure potassium stays in a safe range.

Can Perindosyl AM 5mg/4mg Tablet cause a cough?

Affirmative, a persistent dry cough is a known side effect of perindopril, which is part of Perindosyl AM 5mg/4mg Tablet. If the cough becomes bothersome, your doctor may suggest an alternative treatment.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

Disclaimer:

Getomeds primary intention is to ensure that its consumers get information that is reviewed by experts, accurate, and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all of your concerns about any disease or medication. Do not disregard or postpone seeking professional medical advice because of something you read on Getomeds. Our mission is to support, not replace, the doctor-patient relationship.