Pegmac NT Tablet

Last Updated: December 13th, 2025

Pegmac NT Tablet is a product of Klingen Life Sciences Pvt Ltd

Composition: Gabapentin (300mg) + Nortriptyline (10mg)

₹ 261.56

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

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All Details About Pegmac NT Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Pegmac NT Tablet

Description:

Pegmac NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Pegmac NT Tablet is taken by mouth, with or without food and preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor as it may worsen your symptoms.
Some common side effects of this medicine constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Remember to inform the doctor if you develop any unusual changes in mood as this medicine may lead to suicidal thoughts.
Earlier taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses:

Treatment of Neuropathic pain

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pegmac NT Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Pegmac NT

Sleepiness
Fatiguedness
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Increased heart rate
Uncoordinated body movements
Constipation
Challengingy in urination
Weight gain
Dizziness
Blurred vision
Decreased white blood cell count
Peripheral edema
Weakness
Dryness in mouth
Impotence
Indigestion
Insomnia (difficulty in sleeping)

Warning & Precautions:

Alcohol

CAUTION

Alcohol should be used with caution while taking Pegmac NT Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Pegmac NT Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pegmac NT Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Pegmac NT Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pegmac NT Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pegmac NT Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Employ of Pegmac NT Tablet is not recommended in patients with severe liver disease.

FAQs:

What is Pegmac NT Tablet?

Pegmac NT Tablet is a combination of two medicines: Gabapentin and Nortriptyline. This medicine is useful in the treatment of nerve pain (Neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, it decreases the pain sensation.

Can I stop taking Pegmac NT Tablet when my pain is relieved?

No, you should not stop taking Pegmac NT Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pegmac NT Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.

How to manage weight gain associated with the use of Pegmac NT Tablet?

Pegmac NT Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Can the use of Pegmac NT Tablet affect my sexual life?

The use of Pegmac NT Tablet can affect the sexual life of both men and women. Most commonly observed problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Pegmac NT Tablet.

Are there any serious side effects associated with the use of Pegmac NT Tablet?

Earnest side effects because of Pegmac NT Tablet are uncommon and rare. Consult your doctor immediately if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.

How long will the Pegmac NT Tablet take to act?

An initial benefit with Pegmac NT Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.

What if I forget to take Pegmac NT Tablet?

If you forget to take the scheduled dose of Pegmac NT Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect due to overdosage. If you are not sure what to do, ask your doctor about taking Pegmac NT Tablet.

What if I take too much of this drug by mistake?

In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Overdose of this medicine may make you feel drowsy, weak, unsteady when walking, have double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.

Is there anything I need to avoid while taking Pegmac NT Tablet?

Pegmac NT Tablet may impair your thinking or reactions. Be careful while driving or while doing any activity that requires you to be alert. Do not drink alcohol while you are taking Pegmac NT Tablet. It can increase the effects of alcohol which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Employ of Pegmac NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.

How often should I see the doctor?

You may need to see your doctor regularly if you have started to take Pegmac NT Tablet. However, you must consult your doctor if the advised dosage of Pegmac NT Tablet does not improve your symptoms or you continue experiencing unwanted side effects that affect your routine activities.

Can the use of Pegmac NT Tablet cause sleepiness or drowsiness?

Affirmative, Pegmac NT Tablet may make you feel drowsy or may cause you to suddenly fall asleep during your daily activities. You might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Will Pegmac NT Tablet be more effective if taken more than recommended dose?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the storage condition for Pegmac NT Tablet?

Retain your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and out of reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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