Naprozol 375mg/20mg Tablet

Last Updated: April 10th, 2026

Naprozol 375mg/20mg Tablet is a product of General Pharmaceuticals Pvt Ltd

Composition: Naproxen (375mg) + Esomeprazole (20mg)

₹ 61.15

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Banned For Sale

All Details About Naprozol 375mg/20mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Naprozol 375mg/20mg Tablet

Description:

Naprozol 375mg/20mg Tablet is a combination medicine which helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Naprozol 375mg/20mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include headache, nausea, vomiting, diarrhea, indigestion, flatulence, and stomach pain. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Earlier taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses:

Pain relief

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Naprozol 375mg/20mg Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Naprozol

Headache
Nausea
Vomiting
Diarrhea
Indigestion
Flatulence
Stomach pain
Flu-like symptoms

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Naprozol 375mg/20mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Naprozol 375mg/20mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

UNSAFE

Naprozol 375mg/20mg Tablet may cause side effects that could affect your ability to drive.
Naprozol 375mg/20mg Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.

Kidney

CAUTION

Naprozol 375mg/20mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Naprozol 375mg/20mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is Naprozol 375mg/20mg Tablet used for?

Naprozol 375mg/20mg Tablet is used to relieve pain and inflammation in conditions like arthritis. Naproxen in Naprozol 375mg/20mg Tablet helps relieve pain, and esomeprazole in Naprozol 375mg/20mg Tablet helps protect the stomach lining from ulcers that naproxen alone might cause.

Who should not take Naprozol 375mg/20mg Tablet?

Individuals should not take Naprozol 375mg/20mg Tablet if they are allergic to naproxen, esomeprazole, aspirin, or other NSAIDs, or if they have had asthma, hives, or serious allergic reactions after using pain relievers. It should not be used by people with a history of stomach bleeding caused by NSAIDs.

Can Naprozol 375mg/20mg Tablet increase the risk of heart problems?

Affirmative, naproxen in Naprozol 375mg/20mg Tablet may increase the risk of serious heart conditions such as heart attack or stroke, especially with long-term use or in people with existing heart disease.

What precautions should I take before using Naprozol 375mg/20mg Tablet?

Earlier using Naprozol 375mg/20mg Tablet, tell your doctor if you have high blood pressure, high cholesterol, diabetes, heart disease, kidney disease, liver disease, or if you smoke. These conditions may increase your risk of serious side effects.

Can Naprozol 375mg/20mg Tablet cause stomach bleeding?

Affirmative, naproxen in Naprozol 375mg/20mg Tablet can cause stomach ulcers and bleeding. The esomeprazole in Naprozol 375mg/20mg Tablet helps reduce this risk, but it does not completely prevent it. Watch for warning signs like black stools, vomiting blood, or severe stomach pain.

Are there any serious side effects of Naprozol 375mg/20mg Tablet?

Earnest side effects of Naprozol 375mg/20mg Tablet include heart attack, stroke, kidney failure, liver injury, severe allergic reactions, and bleeding in the stomach or intestines. Get immediate medical help if you notice chest pain, shortness of breath, sudden weakness, or yellowing of the skin.

What signs should I watch for that mean I should stop Naprozol 375mg/20mg Tablet immediately?

Stop taking Naprozol 375mg/20mg Tablet and call your doctor if you develop chest pain, sudden weakness, shortness of breath, black stools, vomiting blood, unexplained weight gain, swelling of the body, or severe skin reactions.

Is long-term use of Naprozol 375mg/20mg Tablet safe?

Long-term use of Naprozol 375mg/20mg Tablet can increase the risk of serious heart, kidney, and stomach problems. Doctors usually prescribe the lowest effective dose for the shortest time needed to reduce risks.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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