Manitol 20% Infusion 350.0 ml in 1 bottle

Last Updated: April 2nd, 2026

Manitol 20% Infusion is a product of Otsuka Pharmaceutical India Pvt Ltd

Composition: Mannitol (20% w/v)

Pack of 350 ml

₹ 87.11

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Manitol 20% Infusion

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Manitol 20% Infusion

Description:

Manitol 20% Infusion is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma.

Manitol 20% Infusion works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine include nausea, vomiting, headache, and dehydration. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually subside on their own after some time. Please consult your doctor if these do not subside or bother you. Regular monitoring by blood tests may be required while using this medicine.

Uses:

Glaucoma
Acute renal failure
Cerebral edema (accumulation of excessive fluid in the brain)

Directions For Use:

Your doctor or nurse will give you this medicine. Compassionately do not self-administer.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Manitol

Nausea
Vomiting
Headache
Dehydration
Injection site reactions (pain, swelling, redness)

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Manitol 20% Infusion. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Manitol 20% Infusion during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Manitol 20% Infusion during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Manitol 20% Infusion is intended for use in hospitalized patients.

Kidney

CAUTION

Manitol 20% Infusion should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Manitol 20% Infusion should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

What is Manitol 20% Infusion used for?

Manitol 20% Infusion is used to help remove extra fluid from your body. It is often given in hospitals to reduce pressure in the brain (after injury or surgery) or in the eyes (like in glaucoma). It can also help your kidneys produce urine when they are not working well and help flush out certain poisons from the body.

Who should not receive Manitol 20% Infusion?

Individuals should not receive Manitol 20% Infusion if they have severe kidney problems, heart failure, lung congestion, severe dehydration, or active bleeding inside the brain (except during surgery). It should also be avoided if the individual is allergic to mannitol.

Is Manitol 20% Infusion safe for people with kidney problems?

Manitol 20% Infusion should be used with great care if your kidneys are not working well. Your doctor may give a small test dose first to check if your kidneys can handle it. If you stop passing urine or your kidney function worsens, the treatment is usually stopped immediately.

Can Manitol 20% Infusion cause brain swelling or confusion?

In some people, Manitol 20% Infusion can cross into the brain and cause confusion, drowsiness, or even worsen swelling in certain cases, especially if the protective barrier between the brain and blood is damaged. Your doctor will monitor you closely to avoid this.

What serious side effects of Manitol 20% Infusion should I watch for?

Earnest side effects of Manitol 20% Infusion may include difficulty breathing, chest pain, confusion, reduced urination, or swelling in your feet. These can be signs of fluid overload, heart failure, or kidney problems, which require medical attention.

Why is Manitol 20% Infusion used to lower pressure in the brain and eyes?

Manitol 20% Infusion helps draw excess fluid out of tissues into the bloodstream, reducing swelling and pressure in the brain and eyes. It is commonly used in emergencies like head injury, stroke, or glaucoma when other treatments are not enough.

Can Manitol 20% Infusion affect my body’s water and salt balance?

Affirmative, Manitol 20% Infusion can change your body’s water and electrolyte levels, sometimes leading to dehydration, high or low sodium, or acid‑base imbalance. Doctors check your blood and urine regularly to keep this in control.

What happens if Manitol 20% Infusion builds up in the body?

If Manitol 20% Infusion is not removed properly by the kidneys, it can build up, causing too much fluid in the body, swelling, or even worsening heart or kidney problems. That is why it is given under close hospital supervision.

Can Manitol 20% Infusion affect people with heart problems?

Affirmative, Manitol 20% Infusion can cause too much fluid in the bloodstream, which may worsen heart failure or cause lung congestion. Doctors will check your heart condition carefully before giving it.

Why do doctors monitor urine output closely during Manitol 20% Infusion?

Urine output helps doctors know if your kidneys are removing Manitol 20% Infusion effectively. Low or no urine during treatment may mean your kidneys are not tolerating it, and the infusion might need to be stopped.

Is Manitol 20% Infusion safe for older adults or children?

Older adults and children may be more sensitive to fluid or electrolyte imbalances caused by Manitol 20% Infusion. The dose is adjusted carefully based on age, weight, and medical condition.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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