Lupex-Plus Tablet 10.0 tablets in 1 strip

Last Updated: March 31st, 2026

Lupex-Plus Tablet is a product of Solarium Pharmaceuticals

Composition: Duloxetine (20mg) + Methylcobalamin (750mcg)

Pack of 10 tablet

₹ 281.20

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Limited Stock

All Details About Lupex-Plus Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Lupex-Plus Tablet

Description:

Lupex-Plus Tablet is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibres against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.

Lupex-Plus Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.

Some common side effects of this medicine include nausea, constipation, headache, insomnia (difficulty in sleeping), ejaculation disorder, erectile dysfunction, and low sexual desire. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

You should avoid alcohol while taking Lupex-Plus Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses:

Neuropathic pain

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupex-Plus Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Lupex-Plus

Nausea
Constipation
Headache
Insomnia (difficulty in sleeping)
Ejaculation disorder
Erectile dysfunction
Low sexual desire

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lupex-Plus Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Lupex-Plus Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Lupex-Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Lupex-Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Lupex-Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.

Liver

UNSAFE

Lupex-Plus Tablet is unsafe to use in patients with liver disease and should be avoided.

FAQs:

What is Lupex-Plus Tablet used for?

Lupex-Plus Tablet is mainly prescribed for treating neuropathic pain (nerve pain), such as that seen in diabetic neuropathy, or other nerve-related issues. Duloxetine in Lupex-Plus Tablet is an antidepressant that reduces nerve pain, while methylcobalamin (active vitamin B12) in Lupex-Plus Tablet helps restore and protect nerve function.

What precautions should I consider before taking Lupex-Plus Tablet?

Earlier taking Lupex-Plus Tablet, tell your doctor if you have a history of liver or kidney disease, glaucoma, mania, or seizures, bleeding disorders, bipolar disorder, or if you drink large amounts of alcohol. Also, mention to your doctor if you are pregnant, breastfeeding, or using other medications.

Who should not use Lupex-Plus Tablet?

Individuals should not use Lupex-Plus Tablet if they are allergic to duloxetine, methylcobalamin, or any other ingredients present in it. Lupex-Plus Tablet must not be taken with medications called monoamine oxidase inhibitors (MAOIs), and it is not recommended for people with severe liver or kidney impairment, or uncontrolled glaucoma (narrow angle).

What are the serious side effects of Lupex-Plus Tablet?

Earnest side effects of Lupex-Plus Tablet include allergic reactions (swelling, rash, trouble breathing), severe skin reactions, liver problems (yellowing of eyes, or skin, dark urine), abnormal mood, or behavior changes (thoughts of self-harm), easy bruising, or signs of serotonin syndrome (agitation, fast heartbeat, hallucinations, muscle stiffness, or vomiting). Perceivek immediate medical help if you experience any of these symptoms.

Is Lupex-Plus Tablet addictive?

No, Lupex-Plus Tablet is not habit-forming or addictive when used as prescribed by your doctor.

How long will Lupex-Plus Tablet take to show benefits, and how long should I keep taking it?

The exact time Lupex-Plus Tablet takes to show benefits is not known. However, relief from nerve pain may begin within a few weeks, but the full effect can take 2 to 4 weeks of regular use. Do not stop taking this medicine suddenly, and always follow your doctor’s advice for starting or stopping Lupex-Plus Tablet.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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