Lorbriqua 25mg Tablet 15.0 tablets in 1 strip

All Details About Lorbriqua 25mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Lorbriqua 25mg Tablet

Description:

Lorbriqua 25mg Tablet is used to treat adults with unresectable (unremovable), advanced, or recurrent forms of non-small cell lung cancer (NSCLC). It works by inhibiting an enzyme called anaplastic lymphoma kinase (ALK) and is given to patients who have an alteration in this enzyme.

Furthermore, Lorbriqua 25mg Tablet is prescribed only to those patients who no longer respond to other ALK inhibitors, such as alectinib or ceritinib. Increaseitionally, it is also effective in treating ALK-positive NSCLC that has spread to the brain.

Take this medicine with or without food, but preferably at the same time each day. Depending on the condition and response to the treatment, the doctor may alter the dose or stop the treatment for a short time. Continue taking this medicine for as long as the doctor has prescribed, and do not stop suddenly.

Some common side effects of Lorbriqua 25mg Tablet include edema (swelling in arms, legs, hands, and feet), peripheral neuropathy (numbness and tingling feeling in joints, arms, and legs), and cognitive disorders (confusion, forgetfulness, and lack of concentration or attention). It may also cause breathlessness, fatigue, weight gain, joint pain, mood changes, and diarrhea. Consult the doctor if any of these side effects are worrisome or worsen. They may adjust the medicine dose and suggest ways to manage them.

Let the doctor know if you have any medical conditions, such as kidney or heart disease, depression, seizures, problems with the heartbeat, or breathing problems. Also, let them know if you have high blood pressure, high levels of cholesterol, or diabetes before starting the treatment with this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medications may affect the working of this tablet; therefore, tell the doctor about all the other medicines you may be taking before starting the treatment with this medicine.

Uses:

Treatment of Non-small cell lung cancer

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lorbriqua 25mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Lorbriqua

Increased triglyceride level in blood
Diarrhea
Cough
Joint pain
Hypercholesterolemia (high cholesterol)
Weight gain
Chubbyigue
Edema (swelling)
High blood pressure
Mood changes
Peripheral neuropathy (tingling and numbness of feet and hand)
Pantingness

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lorbriqua 25mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Lorbriqua 25mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Lorbriqua 25mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Lorbriqua 25mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Lorbriqua 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, no dose adjustment is recommended for patients with mild or moderate renal impairment.

Liver

SAFE IF PRESCRIBED

Lorbriqua 25mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
However, recommended dosage regimen has not been established in cases of moderate to severe hepatic impairment.

FAQs:

What is Lorbriqua 25mg Tablet used for?

Lorbriqua 25mg Tablet is a targeted therapy medicine used to treat non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic). It is specifically for patients whose cancer has a specific genetic mutation called ALK-positive (anaplastic lymphoma kinase-positive).

Is Lorbriqua 25mg Tablet effective for lung cancer patients who have failed previous ALK therapies?

Affirmative, Lorbriqua 25mg Tablet is especially designed for ALK-positive NSCLC patients whose cancer has worsened despite earlier treatments with ALK inhibitors like crizotinib, ceritinib, or alectinib. It is known for its ability to work even after resistance to these anticancer medicines develops.

Can Lorbriqua 25mg Tablet cause serious mental or mood changes?

Affirmative, Lorbriqua 25mg Tablet affects your brain and mood. Some patients may experience confusion, memory problems, mood swings, hallucinations, or speech difficulties. Forever inform your doctor if you notice unusual changes in thinking, sleep, or behavior.

Is it safe to take Lorbriqua 25mg Tablet if I am pregnant or planning to become pregnant?

No, Lorbriqua 25mg Tablet may harm an unborn baby. Women of childbearing potential should use a non-hormonal birth control method during treatment and for at least 35 days after stopping. Men should also use effective contraception for 14 weeks after stopping Lorbriqua 25mg Tablet.

Can Lorbriqua 25mg Tablet cause high cholesterol or triglyceride levels?

Affirmative, Lorbriqua 25mg Tablet can significantly raise cholesterol and triglyceride levels in your blood. Doctors may prescribe lipid-lowering medicines to manage this. Regular blood tests will be needed to monitor your lipid profile during treatment.

Can Lorbriqua 25mg Tablet cause heart problems?

Affirmative, Lorbriqua 25mg Tablet can cause heart rhythm issues such as atrioventricular (AV) block or PR interval prolongation. Your doctor may perform ECG tests before and during Lorbriqua 25mg Tablet treatment, especially if you have a history of heart disease.

What are the warning signs of serious lung problems from Lorbriqua 25mg Tablet?

If you develop symptoms like shortness of breath, coughing, or fever, it may indicate lung inflammation (pneumonitis or ILD), which is a rare but serious side effect of Lorbriqua 25mg Tablet. Inform your doctor immediately if you experience any of these symptoms, as treatment may need to be stopped.

How long does it take for Lorbriqua 25mg Tablet to work?

The time it takes to see results varies from person to person. Some patients may notice improvement within a few weeks, while others may take longer. Your doctor will monitor your progress through regular check-ups and scans.

Can I stop taking Lorbriqua 25mg Tablet if I feel better?

No, do not stop taking Lorbriqua 25mg Tablet without consulting your doctor. Stopping the medication abruptly can cause the cancer to grow or spread. Forever follow your doctor’s instructions.

Can Lorbriqua 25mg Tablet cure my cancer?

Lorbriqua 25mg Tablet is not a cure for cancer, but it can help control the growth and spread of ALK-positive non-small cell lung cancer. It may improve symptoms and prolong survival in some patients.

Will I need regular tests during Lorbriqua 25mg Tablet treatment?

Affirmative, your doctor will likely advise regular blood tests, scans, and check-ups to monitor your response to the treatment and check for any side effects.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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