Lefunol 20 Tablet 10.0 tablets in 1 strip

Last Updated: April 1st, 2026

Lefunol 20 Tablet is a product of Knoll Pharmaceuticals Ltd

Composition: Leflunomide (20mg)

Pack of 10 tablet

₹ 222.19

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Limited Stock

All Details About Lefunol 20 Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Lefunol 20 Tablet

Description:

Lefunol 20 Tablet is used in the treatment of rheumatoid arthritis. It helps in slowing down the progression of the disease and provides relief from pain, swelling, and redness associated with the condition.

Lefunol 20 Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Retain taking it as recommended by your doctor and complete the dose even if you feel better.

Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or affecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses:

Treatment of Rheumatoid arthritis

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefunol 20 Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Lefunol

Headache
Weight loss
High blood pressure
Skin disorder
Musculoskeletal (bone, muscle or joint) pain
Paresthesia (tingling or pricking sensation)
Dizziness

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lefunol 20 Tablet

Pregnancy

UNSAFE

Lefunol 20 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Lefunol 20 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Lefunol 20 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

UNSAFE

Lefunol 20 Tablet is unsafe to use in patients with kidney disease and should be avoided.

Liver

UNSAFE

Lefunol 20 Tablet is unsafe to use in patients with liver disease and should be avoided.

FAQs:

Can Lefunol 20 Tablet cause weight loss?

Affirmative, Lefunol 20 Tablet may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this weight reduction could be due to the accompanying loss of appetite. Consult your doctor if your weight loss is significant.

When should patients notify their doctor?

The doctor should be informed if one has lung problems like cough, shortness of breath, or if one observes symptoms of infection like fever, weakness, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives, rashes, and liver problems like yellowing of skin, loss of appetite, then they should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count, causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.

Can I plan a pregnancy after stopping Lefunol 20 Tablet?

Lefunol 20 Tablet takes a fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Lefunol 20 Tablet. This extensive time duration may be reduced to a few weeks by taking certain medicines, which can help speed up the removal of Lefunol 20 Tablet from your body.

How long does it take to see improvement after starting Lefunol 20 Tablet?

Lefunol 20 Tablet may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor, who will analyze the condition.

Can Lefunol 20 Tablet cause cancer?

Lefunol 20 Tablet may increase your chances of cancer, especially of the lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Lefunol 20 Tablet. Discuss with your doctor if you have concerns regarding it.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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