Lapalieva Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer.
Lapalieva Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine.
Earlier taking Lapalieva Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lapalieva Tablet is to be taken on an empty stomach.
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youβre worried about them
Ordinary side effects of Lapalieva
Abdominal pain
Posterior pain
Breathing problems
Constipation
Cough
Diarrhea
Chubbyigue
Headache
Hot flashes
Increased bilirubin in the blood
Insomnia (difficulty in sleeping)
Joint pain
Liver damage
Loss of appetite
Mucosal inflammation
Nausea
Pain in extremities
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weakness
Weight gain
Warning & Precautions:
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lapalieva Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lapalieva Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Lapalieva Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Lapalieva Tablet may cause side effects that could affect your ability to drive.
Kidney
CAUTION
Lapalieva Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. Limited information is available on the use of Lapalieva Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Lapalieva Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed. Limited information is available on the use of this medicine in patients with the severe liver disease.
FAQs:
Is Lapalieva Tablet a chemotherapy medicine?
No, this is a targeted drug that belongs to a class of anti-cancer medicines. They are more specific than chemotherapy in their mechanisms of action. Lapalieva Tablet belongs to the tyrosine kinase inhibitors group of medicines. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.
Can Lapalieva Tablet be given in combination with other anti-cancer drug?
Affirmative, Lapalieva Tablet can be used with other anti-cancer drugs. Generally, it is used in combination with capecitabine to treat advanced breast cancer in patients who have already been treated with chemotherapy. Lapalieva Tablet is also used with letrozole to treat breast cancer in post-menopausal women.
How should I take Lapalieva Tablet?
You should take Lapalieva Tablet exactly as advised by your doctor. Swallow Lapalieva Tablet tablets whole with a glass of water, at the same time each day. You must take Lapalieva Tablet 1 hour before or 1 hour after meals and at the same time concerning food each day (e.g., you could always take your tablet one hour before breakfast).
Does Lapalieva Tablet have any effect on liver?
Lapalieva Tablet may cause liver damage which can be severe or life-threatening. Liver damage can occur as soon as several days or as late as several months after the start of treatment with Lapalieva Tablet. Inform your doctor if you have or had liver disease. If you experience any of the symptoms such as itching, change in color of the skin or eyes (yellowing), discoloration of urine, pain in the upper right part of the stomach, unusual bleeding or bruising, or pale or dark stools, call your doctor immediately.
How should I manage diarrhea while taking Lapalieva Tablet?
If you suffer from diarrhea while taking Lapalieva Tablet, you should drink plenty of fluids (8 to 10 glasses a day) such as water, sports drinks, or other clear liquids. You should eat low-fat, high protein foods instead of fatty or spicy foods. Eating cooked vegetables instead of raw vegetables and removing the skin from fruits before eating can also be helpful. Try to avoid milk and milk products (including ice cream) and herbal supplements (some may cause diarrhoea). Inform the doctor, if the condition persists, who may interrupt the treatment depending on the severity of diarrhea.
How can I take care of my skin while on Lapalieva Tablet?
Your doctor will check your skin before and during the treatment. If you have sensitive skin, use a soap-free cleanser and beauty products that are fragrance-free and hypoallergenic. It is also advised that you use sunscreen with an SPF (Sun Protection Factor) of 30 or higher. Inform your doctor immediately if you get a rash.
What tests will the doctor advise before starting Lapalieva Tablet?
You may need extra tests to check that your heart and liver are working properly. Lapalieva Tablet may change the way your heart beats and pumps blood through your body. Your doctor will monitor you carefully to see whether Lapalieva Tablet has affected your heart. Along with that, your doctor will get your liver function investigated. Meand on the results of these tests, the doctor will decide whether dose adjustment or discontinuation of treatment is required.
How long after Lapalieva Tablet can I plan pregnancy?
Employ an effective method of contraception to avoid pregnancy while you are taking Lapalieva Tablet and continue for at least 1 week after the last dose. Inform your doctor if you become pregnant, who will decide whether to stop or continue treatment.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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