Knilonat 200 Capsule 10.0 capsules in 1 strip

All Details About Knilonat 200 Capsule

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Knilonat 200 Capsule

Description:

Knilonat 200 Capsule is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Knilonat 200 Capsule should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, nausea, abdominal pain, and rash are very common side effects of this medicine. If you experience severe diarrhea, consult with your doctor or drink plenty of fluids while on treatment. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels and blood sugar or fat level in the body.

Earlier taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Employ of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses:

Blood cancer (Chronic myeloid leukaemia)

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Knilonat 200 Capsule is to be taken empty stomach.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Knilonat

Headache
Nausea
Abdominal pain
Rash
Itching
Hair loss
Muscle pain
Chubbyigue

Warning & Precautions:

Alcohol

SAFE

Consuming alcohol with Knilonat 200 Capsule does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Knilonat 200 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Knilonat 200 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Knilonat 200 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Knilonat 200 Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Knilonat 200 Capsule may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Knilonat 200 Capsule should be used with caution in patients with liver disease. Dose adjustment of Knilonat 200 Capsule may be needed. Please consult your doctor.

FAQs:

What is Knilonat 200 Capsule used for?

Knilonat 200 Capsule is a prescription medicine used to treat a type of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It is used in both newly diagnosed patients and those who did not respond well to other anti-cancer treatments like imatinib.

How does Knilonat 200 Capsule work in treating leukemia?

Knilonat 200 Capsule is a tyrosine kinase inhibitor (TKI). It works by blocking abnormal signals in cancer cells, stopping them from growing. This helps reduce the number of leukemia cells in your body.

Who should not take Knilonat 200 Capsule?

Individuals should not take Knilonat 200 Capsule if they have low potassium or magnesium levels, a history of heart rhythm problems (QT prolongation), severe liver problems, or a known allergy to nilotinib or any ingredients present in Knilonat 200 Capsule.

What are the most serious side effects of Knilonat 200 Capsule?

The serious side effects of Knilonat 200 Capsule include sudden cardiac death, QT interval prolongation (heart rhythm issues), liver failure, pancreatitis, and severe low blood counts. Call your doctor right away if you feel faint, dizzy, have chest pain, or severe stomach pain.

What should I tell my doctor before starting Knilonat 200 Capsule?

Earlier starting Knilonat 200 Capsule, let the doctor know if there are heart, liver, or kidney issues. Also, inform if taking medications that affect the heartbeat or liver. Mention if pregnant, planning pregnancy, or breastfeeding.

Can Knilonat 200 Capsule affect my blood cell counts?

Affirmative, Knilonat 200 Capsule can cause low red cells (anemia), white cells (neutropenia), or platelets (thrombocytopenia). Your doctor will monitor your blood regularly during treatment.

Can I take Knilonat 200 Capsule with food or supplements?

It is advised to avoid all food 2 hours before and 1 hour after taking Knilonat 200 Capsule, as food increases Knilonat 200 Capsule absorption, which can raise the risk of side effects. Forever take it on an empty stomach as directed. Also, avoid grapefruit, St. John's Wort, and calcium or magnesium supplements near your dose unless prescribed by your doctor.

Can I ever stop taking Knilonat 200 Capsule?

Possibly, if Knilonat 200 Capsule has been taken for at least 3 years and leukemia is in deep molecular remission (can no longer detect cancer-related genetic markers such as BCR-ABL1 in leukemia in the blood), the doctor may consider discontinuing treatment. Frequent monitoring will be needed to ensure the cancer does not return.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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