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All Details About Jeprax 20mg/ml Injection
Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Jeprax 20mg/ml Injection
Description:
Jeprax 20mg/ml Injection is a pain-relieving medicine. It is used in the treatment of moderate to severe pain. It helps to relieve pain and swelling of various conditions related to joints and muscles. It is usually given in cases where oral administration is unsuitable.Jeprax 20mg/ml Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), vomiting, stomach pain, indigestion, diarrhea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Earlier using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses:
Directions For Use:
Your doctor or nurse will give you this medicine. Compassionately do not self administer.Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themOrdinary side effects of Jeprax
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
Warning & Precautions:
Alcohol
CAUTION
Alcohol should be used with caution while taking Jeprax 20mg/ml Injection.
Pregnancy
CONSULT YOUR DOCTOR
Jeprax 20mg/ml Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CONSULT YOUR DOCTOR
Jeprax 20mg/ml Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Jeprax 20mg/ml Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Jeprax 20mg/ml Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Jeprax 20mg/ml Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
FAQs:
What is the difference between Jeprax 20mg/ml Injection and diclofenac?
Both Jeprax 20mg/ml Injection and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Jeprax 20mg/ml Injection.
What is the difference between Jeprax 20mg/ml Injection and naproxen?
Both Jeprax 20mg/ml Injection and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Jeprax 20mg/ml Injection.
What is the difference between Jeprax 20mg/ml Injection and meloxicam?
Both Jeprax 20mg/ml Injection and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Jeprax 20mg/ml Injection.
What is the difference between Jeprax 20mg/ml Injection and ketoprofen?
Both Jeprax 20mg/ml Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Jeprax 20mg/ml Injection. Ketoprofen gel also showed excellent tolerability.
What is the difference between Jeprax 20mg/ml Injection and tramadol?
Jeprax 20mg/ml Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
What is the difference between Jeprax 20mg/ml Injection and nimesulide?
Both Jeprax 20mg/ml Injection and nimesulide are pain killers. However, Jeprax 20mg/ml Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can Jeprax 20mg/ml Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Jeprax 20mg/ml Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Jeprax 20mg/ml Injection.
Are Jeprax 20mg/ml Injection and aspirin same?
No. Jeprax 20mg/ml Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Jeprax 20mg/ml Injection be used along with dexamethasone?
No. Jeprax 20mg/ml Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Can Jeprax 20mg/ml Injection be used with methocarbamol?
Affirmative. Methocarbamol can be used with Jeprax 20mg/ml Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Can Jeprax 20mg/ml Injection be used along with paracetamol?
Affirmative. Paracetamol can be used with Jeprax 20mg/ml Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Is Jeprax 20mg/ml Injection a NSAID?
Affirmative. Jeprax 20mg/ml Injection is a non-steroidal anti-inflammatory drug (NSAID).
Is Jeprax 20mg/ml Injection a sulfa drug?
Jeprax 20mg/ml Injection is a sulphur containing compound. Jeprax 20mg/ml Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Is Jeprax 20mg/ml Injection a blood thinner?
No. Jeprax 20mg/ml Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Is Jeprax 20mg/ml Injection a muscle relaxant?
No. Jeprax 20mg/ml Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Is Jeprax 20mg/ml Injection a narcotic?
No. Jeprax 20mg/ml Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Can Jeprax 20mg/ml Injection be used in hypertension?
No. Jeprax 20mg/ml Injection is not a medication to control hypertension. It is important to note that Jeprax 20mg/ml Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Jeprax 20mg/ml Injection.
Can Jeprax 20mg/ml Injection be used along with Losartan?
No. Jeprax 20mg/ml Injection should not be combined with Losartan. It is important to note that Jeprax 20mg/ml Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Jeprax 20mg/ml Injection.
Can Jeprax 20mg/ml Injection be used with Lisinopril?
No. Jeprax 20mg/ml Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Jeprax 20mg/ml Injection.
Can Jeprax 20mg/ml Injection be used with calcium channel blocker?
Affirmative. Jeprax 20mg/ml Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Can Jeprax 20mg/ml Injection be used with Tizanidine?
Affirmative, Jeprax 20mg/ml Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Why is beta cyclodextrin added to Jeprax 20mg/ml Injection?
Affirmative. Jeprax 20mg/ml Injection can be combined with beta-cyclodextrin. Research has shown that combining Jeprax 20mg/ml Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Are there any alternatives of Jeprax 20mg/ml Injection?
Affirmative. There are alternatives to Jeprax 20mg/ml Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
What are the contraindications for Jeprax 20mg/ml Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Can Jeprax 20mg/ml Injection be used in the treatment of allergy?
No. Jeprax 20mg/ml Injection is not a drug to treat allergy. It is a pain killer.
How long does Jeprax 20mg/ml Injection work?
Jeprax 20mg/ml Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can you get high by using Jeprax 20mg/ml Injection?
No. Jeprax 20mg/ml Injection is not known to cause high. It is a non-narcotic painkiller.
Can Jeprax 20mg/ml Injection be used to treat menstrual cramp?
Jeprax 20mg/ml Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Can I use Jeprax 20mg/ml Injection for a migraine?
Jeprax 20mg/ml Injection is not approved for the treatment of migraine. Research studies have shown that Jeprax 20mg/ml Injection is effective in significantly decreasing the pain associated with migraine without aura.
Is Jeprax 20mg/ml Injection effective in back pain management?
Affirmative. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Jeprax 20mg/ml Injection as the cause of back pain can be different for different person.
Is Jeprax 20mg/ml Injection affective in gout management?
Affirmative. Jeprax 20mg/ml Injection can be given for the treatment of acute gout. Research studies have shown Jeprax 20mg/ml Injection to be highly effective in the treatment of acute gout.
Can you donate blood when on the medication with Jeprax 20mg/ml Injection?
Affirmative. You can donate blood when on Jeprax 20mg/ml Injection. Do inform your doctor before donating blood.
Can I use Jeprax 20mg/ml Injection if I am a diabetic?
Jeprax 20mg/ml Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Jeprax 20mg/ml Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Can I use Jeprax 20mg/ml Injection if I have a deranged renal function?
No. Jeprax 20mg/ml Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Can Jeprax 20mg/ml Injection lead to skin reactions?
Affirmative. Jeprax 20mg/ml Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Can I use Jeprax 20mg/ml Injection if I am pregnant?
No. Jeprax 20mg/ml Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can I use Jeprax 20mg/ml Injection if I have peptic ulcer disease?
No. Jeprax 20mg/ml Injection is contraindicated in cases of active peptic ulcer disease. Jeprax 20mg/ml Injection is known to cause gastric ulceration and bleeding.
Can I use Jeprax 20mg/ml Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Can Jeprax 20mg/ml Injection lead to difficulty in conception?
Affirmative. Jeprax 20mg/ml Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Can Jeprax 20mg/ml Injection be used with diuretics?
No. Jeprax 20mg/ml Injection should not be used with diuretics. Jeprax 20mg/ml Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can Jeprax 20mg/ml Injection be used with lithium?
No. Jeprax 20mg/ml Injection should not be used with lithium. Jeprax 20mg/ml Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Jeprax 20mg/ml Injection be used with warfarin?
No. Jeprax 20mg/ml Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
What increases the chances of getting a gastric ulcer when I am already taking Jeprax 20mg/ml Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Jeprax 20mg/ml Injection?
Tolerants who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
What are the serious side effects of Jeprax 20mg/ml Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)
Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H
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