JakAVI 5mg Tablet 10.0 tablets in 1 strip

All Details About JakAVI 5mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about JakAVI 5mg Tablet

Description:

JakAVI 5mg Tablet is a medicine used to treat certain blood disorders, mainly chronic idiopathic myelofibrosis and polycythemia vera. These conditions affect how bone marrow makes blood cells. It works by blocking specific enzymes that play a key role in the signals that control blood cell production.

JakAVI 5mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Earlier taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

There is a Tolerant Support Program/Tolerant Assistance Program available in India for this medicine, being managed by Tata . Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses:

Treatment of Chronic idiopathic myelofibrosis
Treatment of Polycythemia vera

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. JakAVI 5mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of JakAVI

Anemia (low number of red blood cells)
Low blood platelets
Dizziness
Infection
Headache
Chubbyigue
Decreased white blood cell count (neutrophils)
Increased alanine aminotransferase
Bruising

Warning & Precautions:

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with JakAVI 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

JakAVI 5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

JakAVI 5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether JakAVI 5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

JakAVI 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Employ of JakAVI 5mg Tablet is not advised in patients with moderate to severe kidney disease.

Liver

CAUTION

JakAVI 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

FAQs:

What is JakAVI 5mg Tablet used for?

JakAVI 5mg Tablet is prescribed to treat certain blood disorders such as myelofibrosis and polycythemia vera. It may also be used in graft-versus-host disease (in individuals aged 12 years and older). It works by reducing abnormal blood cell activity and easing symptoms such as an enlarged spleen, night sweats, and itching.

Who should not take JakAVI 5mg Tablet?

There are no absolute contraindications listed, but JakAVI 5mg Tablet should not be used in individuals with uncontrolled infections or very low blood counts unless a doctor determines that the benefits outweigh the risks. Forever consult your doctor before starting this medicine.

Can JakAVI 5mg Tablet increase the risk of infections?

Affirmative. JakAVI 5mg Tablet can weaken your immune system and increase the risk of serious infections, including tuberculosis, shingles, and bacterial or viral illnesses. Report any fever, cough, painful skin rash, or unusual symptoms to your doctor immediately.

Can stopping JakAVI 5mg Tablet suddenly be dangerous?

Affirmative. Stopping JakAVI 5mg Tablet suddenly may cause your symptoms—such as spleen pain or blood abnormalities—to return quickly or worsen. Do not discontinue this medicine on your own. Your doctor may reduce the dose gradually if needed.

Can JakAVI 5mg Tablet cause low blood counts?

JakAVI 5mg Tablet may cause anemia (low red blood cells), thrombocytopenia (low platelets), or neutropenia (low white blood cells). These conditions can increase the risk of bleeding, fatigue, or infections. Your doctor will monitor your blood counts regularly during treatment.

Does JakAVI 5mg Tablet increase the risk of skin cancer?

Affirmative. JakAVI 5mg Tablet may increase the risk of non-melanoma skin cancers such as basal cell carcinoma or squamous cell carcinoma. Regular skin examinations and sun protection are recommended while using this medicine.

Can JakAVI 5mg Tablet affect cholesterol levels?

JakAVI 5mg Tablet may raise cholesterol levels. Your doctor will monitor your lipid profile during treatment and may prescribe medication if needed to manage it.

Can JakAVI 5mg Tablet cause blood clots?

Affirmative. Some individuals taking JakAVI 5mg Tablet may develop blood clots in the veins or arteries. If you experience sudden leg pain, swelling, chest pain, or difficulty breathing, seek medical attention immediately.

Does JakAVI 5mg Tablet increase the chance of other cancers?

Affirmative, JakAVI 5mg Tablet may increase the risk of developing secondary cancers, especially in people who currently smoke or have smoked in the past. Your doctor will monitor you for signs of new malignancies during long-term treatment.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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