Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Istamet XR
Istamet XR Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.
Istamet XR Tablet may be prescribed alone or along with other diabetes medications. It works best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.
You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istamet XR Tablet is to be taken with food
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Istamet
Q. What is Istamet XR Tablet?
Istamet XR Tablet is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.
Q. Can the use of Istamet XR Tablet lead to Vitamin B12 deficiency?
Yes, the use of Istamet XR Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
Q. What are the possible side effects of Istamet XR Tablet?
The use of Istamet XR Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
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