Isolazine 20mg/37.5mg Tablet 15.0 tablets in 1 strip

Last Updated: October 3rd, 2025

Isolazine 20mg/37.5mg Tablet is a product of Lupin Ltd

Composition: Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg)

Pack of 15 tablet

₹ 216.1

*Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Isolazine 20mg/37.5mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Isolazine 20mg/37.5mg Tablet

Description:

Isolazine 20mg/37.5mg Tablet is used in the treatment of heart failure. It is a combination of two medicines that effectively control symptoms of heart failure.

Isolazine 20mg/37.5mg Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like a low-fat diet, exercise, and not smoking may help this medicine to work better.

It is generally safe and suitable for most people but has some potential side effects. The most common side effects of this medicine include nausea, vomiting, diarrhea, low blood pressure, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes you feel dizzy as of orthostatic hypotension (sudden lowering of blood pressure on standing). Hence, rise slowly while from a sitting position or avoid driving. You may be asked for regular monitoring of blood pressure while on the treatment.

Earlier taking this medicine, tell your doctor if you have liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses:

Treatment of Heart Failure

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isolazine 20mg/37.5mg Tablet is to be taken with food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youâ€™re worried about them

Ordinary side effects of Isolazine

Nausea
Headache
Dizziness
Weakness
Ventricular tachycardia
Paralysis of ileus
Hypotension (low blood pressure)
Visual impairment

Warning & Precautions:

Alcohol

UNSAFE

Consuming alcohol while taking Isolazine 20mg/37.5mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Isolazine 20mg/37.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Isolazine 20mg/37.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Isolazine 20mg/37.5mg Tablet may cause side effects which could affect your ability to drive.
As Isolazine 20mg/37.5mg Tablet may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.

Kidney

CAUTION

Isolazine 20mg/37.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Isolazine 20mg/37.5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

SAFE IF PRESCRIBED

Isolazine 20mg/37.5mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isolazine 20mg/37.5mg Tablet may not be needed in these patients. Please consult your doctor.

FAQs:

Can I stop taking Isolazine 20mg/37.5mg Tablet if I feel well?

No, keep using Isolazine 20mg/37.5mg Tablet as advised by your doctor, even if you feel well. Stopping Isolazine 20mg/37.5mg Tablet suddenly may lead to serious complications of heart failure.

Are there any special instructions regarding storage and disposal of this medicine?

Retain this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Isolazine 20mg/37.5mg Tablet cause headache?

Isolazine 20mg/37.5mg Tablet can frequently cause headaches, especially at the start of the treatment. As the treatment continues, your headache may become less intense and frequent. However, inform your doctor if headache continues.

Can the use of Isolazine 20mg/37.5mg Tablet cause dizziness?

Affirmative, the use of Isosorbide Isolazine 20mg/37.5mg Tablet can make you feel dizzy. This may often occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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