Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet 10.0 tablets in 1 strip

Last Updated: March 28th, 2026

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is a product of Mankind Pharma Ltd

Composition: Sitagliptin (50mg) + Glimepiride (2mg) + Metformin (1000mg)

Pack of 10 tablet

₹ 126.56

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All Details About Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet

Description:

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is a combination of three medicines used to lower blood glucose levels in people with type 2 diabetes mellitus. It is generally prescribed when diet, exercise, and other treatments do not result in adequate glycemic control.

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is best taken with food; however, take this medicine regularly and at the same time each day to get maximum benefits. The dose and duration are decided according to your condition and how well you respond to it. The doctor may also monitor your blood sugar levels regularly when you are taking this combination medicine.

Retain taking this medicine even if you feel well or your blood sugar levels are controlled. If stopped abruptly, your blood sugar levels could rise and put you at risk of complications. This medication is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction because lifestyle habits play a big part in controlling diabetes.

The most common side effects of Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet include nausea, vomiting, gastrointestinal disturbances, and hypoglycemia. Let your doctor know if any of these side effects do not go away or get worse. They may be able to help by adjusting the dosage or by prescribing an alternate medicine.

You should not take Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet if you have type 1 diabetes mellitus or acute or chronic metabolic acidosis, including diabetic ketoacidosis. Tolerants with active bladder cancer or a history of bladder cancer should also not take this medicine. Inform your doctor about all the other medicines that you take as some of them can affect or be affected by this medication. Pregnant or breastfeeding women should also consult their doctors before taking it.

Uses:

Treatment of Type 2 diabetes mellitus

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Glimestar SM

Gastrointestinal disturbance
Headache
Diarrhea
Abdominal pain
Hypoglycemia (low blood glucose level)
Constipation
Vomiting
Nausea

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CAUTION

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

CAUTION

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is unsafe to use in patients with liver disease and should be avoided.

FAQs:

What is Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet used for in diabetes?

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is used to treat type 2 diabetes mellitus in adults when diet and exercise alone or along with other blood sugar-lowering medicines aren’t enough to control blood sugar. It helps lower blood sugar levels, improve insulin response, and reduce the risk of complications from long-term diabetes.

When should I take Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet?

Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet should be taken once or twice daily with meals, depending on your doctor's prescription. Taking the medicine with food reduces the chance of stomach upset and lowers the risk of low blood sugar (hypoglycemia).

Can I take Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet if I have kidney or liver issues?

No. Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet is not recommended for patients with severe kidney or liver problems, as it may increase the risk of lactic acidosis, low blood sugar, or medication buildup in the body. Your doctor will assess kidney function before prescribing.

Are there any side effects of Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet?

The common side effects of Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet may include nausea, upset stomach, diarrhea, or constipation, headache, hypoglycemia (low blood sugar), weight gain, etc. If you experience severe side effects like difficulty breathing, chest pain, or signs of lactic acidosis (e.g., muscle pain, weakness, or dizziness), contact your doctor immediately.

Can I drink alcohol while taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet?

Avoid alcohol while taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet, as it can increase the risk of side effects like hypoglycemia (low blood sugar) or lactic acidosis (a serious condition caused by metformin present in Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet).

How long does it take for Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet to work?

You may start noticing improvements in blood sugar levels within a few days. However, it may take a few weeks to months to see the full benefits.

Can I stop taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet if my blood sugar improves?

No, do not stop taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet without consulting your doctor. Stopping the medication abruptly can cause your blood sugar levels to rise again. Forever follow your doctor's instructions.

What should I avoid while taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet?

Avoid high-sugar or high-carbohydrate foods, as they can affect blood sugar control; limit alcohol consumption, as it can increase the risk of side effects; and avoid skipping meals, as it may lead to low blood sugar, etc.

What tests should I regularly monitor while taking Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet?

While on Glimestar-SM2 Forte 50mg/2mg/1000mg Tablet treatment, your doctor may advise you to regularly check fasting and post-meal blood glucose, HbA1c (every 3 months), kidney and liver function tests, vitamin B12 levels, and weight and blood pressure. These help ensure your diabetes is well managed and prevent complications.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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