Endoxan 500mg Injection 1 Injection in 1 vial

Last Updated: July 24th, 2023

Endoxan 500mg Injection is a product of Zydus Cadila

Composition: Cyclophosphamide (500mg)

Pack of 1 injection

₹ 84.00

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

All Details About Endoxan 500mg Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Endoxan 500mg Injection

Description:

Endoxan 500mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.

Endoxan 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Earlier taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses:

Directions For Use:

Ordinary side effects of Endoxan

Vomiting
Nausea
Hair loss
Fever
Blood in urine
Diarrhea
Decreased white blood cell count (neutrophils)

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Endoxan 500mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

Endoxan 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Endoxan 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Endoxan 500mg Injection may cause side effects which could affect your ability to drive.
Endoxan 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.

Kidney

CAUTION

Endoxan 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan 500mg Injection may be needed. Please consult your doctor.

Liver

CAUTION

Endoxan 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Endoxan 500mg Injection may be needed. Please consult your doctor.

FAQs:

Q. Can Endoxan 500mg Injection cause infertility?

Affirmative, Endoxan 500mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Communicate to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Endoxan 500mg Injection.

Q. Do I need to avoid sun exposure during treatment with Endoxan 500mg Injection?

No, there is no evidence that you need to avoid sun exposure while on Endoxan 500mg Injection. Skin and nail discoloration are reported rarely with Endoxan 500mg Injection.

Q. Can Endoxan 500mg Injection cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Endoxan 500mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Endoxan 500mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Endoxan 500mg Injection chemotherapy medicine?

Affirmative, Endoxan 500mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Endoxan 500mg Injection be used for non-cancer condition?

Affirmative, Endoxan 500mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Endoxan 500mg Injection for nephrotic syndrome has not been established.

Q. Can Endoxan 500mg Injection causes weight loss?

Affirmative, Endoxan 500mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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