Doxedep 25mg Tablet 10.0 tablets in 1 strip

Last Updated: October 7th, 2025

Doxedep 25mg Tablet is a product of Manas Pharma MFG

Composition: Doxepin (25mg)

Pack of 10 tablet

₹ 65.63

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Not Available

All Details About Doxedep 25mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Doxedep 25mg Tablet

Description:

Doxedep 25mg Tablet is a tricyclic antidepressant. It is used in the treatment of insomnia (difficulty in sleeping). It is also used in patients intolerant of or unresponsive to alternative (other) treatment options for depression and anxiety disorders.

Doxedep 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is usually advised to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medicine.

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Earnest side effects associated with this medicine are rare.

Earlier taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

Uses:

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxedep 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Doxedep

Increased heart rate
Blurred vision
Constipation
Challengingy in urination
Dryness in mouth
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weight gain

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Doxedep 25mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Doxedep 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Doxedep 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.

Driving

UNSAFE

Doxedep 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Doxedep 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Doxedep 25mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.

Liver

CAUTION

Doxedep 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Doxedep 25mg Tablet may be needed. Please consult your doctor.

FAQs:

Can I stop taking Doxedep 25mg Tablet abruptly?

No, you should always check with your doctor before you stop taking Doxedep 25mg Tablet. Stopping the medicine abruptly may cause withdrawal effects. So, your doctor may reduce your dose gradually before taking you off the medicine completely. This helps to prevent a recurrence of the symptoms of depression and also reduces the chances of withdrawal symptoms.

Does Doxedep 25mg Tablet cause withdrawal symptoms?

Affirmative, stopping the use of Doxedep 25mg Tablet abruptly results in withdrawal symptoms which include insomnia (trouble falling asleep), irritability and excessive sweating. You should consult your doctor if you need to stop Doxedep 25mg Tablet. You doctor may gradually reduce the dose of Doxedep 25mg Tablet before taking you off Doxedep 25mg Tablet completely.

When must Doxedep 25mg Tablet not be taken?

You should not take Doxedep 25mg Tablet if you have ever had an allergic reaction to antidepressant medicines (such as Doxedep 25mg Tablet), or any of the inactive ingredients of Doxedep 25mg Tablet. Avoid taking Doxedep 25mg Tablet if you have glaucoma (increased eye pressure), liver problems, any difficulty in passing urine, if you are pregnant or breastfeeding. Do not take Doxedep 25mg Tablet if you are taking or have taken monoamine oxidase inhibitors (MAOIs) in the last two weeks or, if you suffer from mania (where you experience an abnormally elevated and excitable mood). It should not be given to children under 12 years of age.

Can I drive while on Doxedep 25mg Tablet treatment?

Taking Doxedep 25mg Tablet may cause sleepiness, so you should avoid driving or working with machinery until the effect has worn off. Driving while taking Doxedep 25mg Tablet may increase the risk of sleep-driving. This refers to driving while not fully awake after taking a sleeping medicine that can lead to decreased awareness of the surroundings and cause accidents.

What are the overdose symptoms of Doxedep 25mg Tablet?

Overdose of Doxedep 25mg Tablet can be mild or severe. Signs and symptoms of mild overdose include drowsiness, blurred vision and excessive dryness of the mouth. Severe overdose may cause loss of consciousness, difficulty breathing, convulsions, low blood pressure, unusually fast heartbeat or palpitations. If you take too much of Doxedep 25mg Tablet, contact your doctor immediately or seek emergency medical help.

How long does it take for Doxedep 25mg Tablet to kick in?

It may take several weeks or longer for you to experience significant benefits of Doxedep 25mg Tablet. Do not stop taking Doxedep 25mg Tablet without talking to your doctor, even if you feel better.

Can Doxedep 25mg Tablet treat insomnia?

Affirmative. Doxedep 25mg Tablet is also used for the treatment of insomnia (difficulty sleeping). It is especially helpful for people who have trouble staying asleep.

Can I drink alcohol while on treatment with Doxedep 25mg Tablet?

No, you should not drink alcohol while taking Doxedep 25mg Tablet as alcohol can increase the sleepiness or dizziness that occur as side effects of Doxedep 25mg Tablet.

Is Doxedep 25mg Tablet addictive?

Generally Doxedep 25mg Tablet does not cause dependence and is therefore not addictive. But, you should not stop taking Doxedep 25mg Tablet abruptly as it may cause temporary withdrawal symptoms such as insomnia (trouble falling asleep), irritability and excessive sweating.

Can Doxedep 25mg Tablet cause suicidal thoughts?

Affirmative, Doxedep 25mg Tablet can cause suicidal thoughts. This is more common in people who have previously had thoughts about killing or harming themselves, are younger than 25 years of age with a history of psychiatric conditions and who have earlier been treated with an antidepressant. If you experience suicidal thoughts, contact your doctor or go to a hospital straight away. You may also find it helpful to talk to a relative or close friend.

Does Doxedep 25mg Tablet cause weight gain or loss of appetite?

Doxedep 25mg Tablet may cause weight gain as well as loss of appetite, but it is not very common. Call your doctor if any of these bother you.

What is the best time to take Doxedep 25mg Tablet?

Doxedep 25mg Tablet should be taken in the dose and duration advised by the doctor. Your dose will depend on the illness you are being treated for. If you are taking Doxedep 25mg Tablet for insomnia, you should take it 30 minutes just before bedtime and you should not do anything that needs mental focus. If you are taking it for depression or anxiety, take it exactly as directed by your doctor. Remember to take this medicine at the same time each day to avoid missing doses.

What are the side effects of Doxedep 25mg Tablet?

The side effects of Doxedep 25mg Tablet include increased heart rate, weight gain, dryness in mouth, orthostatic hypotension (sudden lowering of blood pressure on standing), constipation and difficulty in urination. It may make your skin more sensitive to sunlight, cause chills and excessive sweating. Please consult your doctor if any of these side effects worry you or do not go away.

Written by:
Dr. Lokanish
M.B.B.S.

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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