Dolobest SP 100mg/500mg/15mg Tablet 10.0 tablets in 1 strip

Last Updated: March 27th, 2026

Dolobest SP 100mg/500mg/15mg Tablet is a product of TTK Healthcare Ltd

Composition: Aceclofenac (100mg) + Paracetamol (500mg) + Serratiopeptidase (15mg)

Pack of 10 tablet

₹ 68.91

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All Details About Dolobest SP 100mg/500mg/15mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Dolobest SP 100mg/500mg/15mg Tablet

Description:

Dolobest SP 100mg/500mg/15mg Tablet is a combination medicine that relieves muscle, joint, and postoperative pain. It effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Dolobest SP 100mg/500mg/15mg Tablet should be taken at the dose and duration advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the correct times increases its effectiveness. It is important to continue taking it until your doctor tells you it is safe to stop.

Nausea, vomiting, stomach pain, indigestion, heartburn, increased liver enzymes, dizziness, drowsiness, and diarrhea are some common side effects that might be observed on taking this medicine. Your doctor may regularly monitor your kidney function, liver function, and blood component levels if you take this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems. Dolobest SP 100mg/500mg/15mg Tablet is not recommended if you are pregnant or breastfeeding.

Uses:

Pain relief

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dolobest SP 100mg/500mg/15mg Tablet should be taken with or after food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Dolobest SP

Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
Dizziness
Increased liver enzymes
Drowsiness

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Dolobest SP 100mg/500mg/15mg Tablet

Pregnancy

UNSAFE

Dolobest SP 100mg/500mg/15mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Dolobest SP 100mg/500mg/15mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Dolobest SP 100mg/500mg/15mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Dolobest SP 100mg/500mg/15mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Employ of Dolobest SP 100mg/500mg/15mg Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Dolobest SP 100mg/500mg/15mg Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Dolobest SP 100mg/500mg/15mg Tablet is not recommended in patients with severe liver disease and active liver disease.

FAQs:

What is Dolobest SP 100mg/500mg/15mg Tablet?

It combines three medicines: Aceclofenac, Paracetamol, and Serratiopeptidase. This medication relieves pain and inflammation by lowering the levels of chemical substances in the body that cause them.

Is it safe to take Dolobest SP 100mg/500mg/15mg Tablet?

Most patients can safely take this medicine. However, some may experience unwanted side effects, such as nausea, vomiting, stomach pain, heartburn, and diarrhea. If you experience persistent problems due to the medication, inform your doctor immediately.

Can I stop taking Dolobest SP 100mg/500mg/15mg Tablet when my pain is relieved?

This medicine is usually used for the short term and can be discontinued when your pain is relieved. However, if your doctor has advised you to continue taking it, do so.

Can Dolobest SP 100mg/500mg/15mg Tablet cause nausea and vomiting?

Affirmative, the use of this medicine can cause nausea and vomiting. In case you experience nausea while taking this medicine, take it with milk, food, or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small, frequent sips. Communicate to your doctor if vomiting persists, and you notice signs of dehydration, like dark-colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Can Dolobest SP 100mg/500mg/15mg Tablet cause dizziness?

Affirmative, this medicine can cause dizziness (feeling faint, weak, unsteady, or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for a while and resume once you feel better.

Are there any specific contraindications associated with taking Dolobest SP 100mg/500mg/15mg Tablet?

This medicine is considered harmful for patients with known allergies to any of its components, excipients, or other painkillers (NSAIDs). It should preferably be avoided in patients with a history of stomach ulcers or active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Can I take Dolobest SP 100mg/500mg/15mg Tablet with vitamin B-complex?

Affirmative, this medicine can be taken with vitamin B-complex preparations. While it helps relieve pain, vitamin B-complex can help correct the vitamin deficiency that might be causing your symptoms.

Can the use of Dolobest SP 100mg/500mg/15mg Tablet cause damage to kidneys?

Affirmative, long-term use of this medicine can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from harm. The use of painkillers lowers the levels of prostaglandins in the body, which leads to kidney damage on long-term use. The use of painkillers is not recommended in patients with underlying kidney disease.

Can I take a higher dose of Dolobest SP 100mg/500mg/15mg Tablet than recommended?

No, taking a higher-than-recommended dose can lead to increased chances of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the instructions for storage and disposal of Dolobest SP 100mg/500mg/15mg Tablet?

Retain this medicine tightly closed in the packet or container it came in. Store it according to the instructions on the pack or label. Dispose of the unused medicine. Ensure it is not consumed by pets, children, or others.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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