Deprant Plus Tablet

Last Updated: March 30th, 2026

Deprant Plus Tablet is a product of Currant Life Science LLP

Composition: Amitriptyline (12.5mg) + Chlordiazepoxide (5mg)

₹ 35.63

Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes

Restricted

All Details About Deprant Plus Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Deprant Plus Tablet

Description:

Deprant Plus Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Deprant Plus Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Earnest side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses:

Treatment of Depression

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Deprant Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Deprant Plus

Constipation
Challengingy in urination
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Fatiguedness
Blurred vision
Dryness in mouth
Increased heart rate
Uncoordinated body movements
Depression
Memory impairment

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Deprant Plus Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Deprant Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Deprant Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Deprant Plus Tablet may cause side effects which could affect your ability to drive.
As Deprant Plus Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Deprant Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Deprant Plus Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Deprant Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Deprant Plus Tablet may be needed. Please consult your doctor.

FAQs:

Are there any important warnings associated with use of Deprant Plus Tablet?

During the first few months of treatment, Deprant Plus Tablet may increase suicidal thoughts or actions in some patients. Tolerants having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Can I stop taking Deprant Plus Tablet when my symptoms are relieved?

No, you should continue to take Deprant Plus Tablet, even if you feel well. If you stop Deprant Plus Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

How to manage weight gain associated with the use of Deprant Plus Tablet?

There are reports which suggest that the use of Deprant Plus Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Can the use of Deprant Plus Tablet cause sleepiness?

Affirmative, Deprant Plus Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Can the use of Deprant Plus Tablet affect my sexual life?

The use of Deprant Plus Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Can I drink alcohol while taking Deprant Plus Tablet?

No, do not drink alcohol while you are taking Deprant Plus Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Deprant Plus Tablet.

Can the use of Deprant Plus Tablet change the color of urine?

Affirmative, Deprant Plus Tablet can the change the color of the urine to blue or green. This change of color is expected while using Deprant Plus Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Deprant Plus Tablet.

How long does Deprant Plus Tablet take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Deprant Plus Tablet, although some people will start to feel better sooner. When taking Deprant Plus Tablet, it is important to give it time to work.

What are the instructions for storage and disposal of Deprant Plus Tablet?

Retain this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

Disclaimer:

Getomeds primary intention is to ensure that its consumers get information that is reviewed by experts, accurate, and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all of your concerns about any disease or medication. Do not disregard or postpone seeking professional medical advice because of something you read on Getomeds. Our mission is to support, not replace, the doctor-patient relationship.