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Denoclast Injection 1.0 ml in 1 prefilled syringe

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Denoclast Injection is a product of Zydus Biovation

Composition: Denosumab (60mg)

Pack of 1 ml

₹ 19687

*Note: MRP can vary depending up on batch!

*MRP inclusive of all taxes
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All Details About Denoclast Injection

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Denoclast Injection

Description:

Denoclast Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.

Denoclast Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.

Some common side effects of this medicine include headache, pain in extremity, musculoskeletal pain, nerve pain, constipation, and rash. Communicate to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

Uses:

Directions For Use:

Your doctor or nurse will give you this medicine. Compassionately do not self administer.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Denoclast

  • Rash
  • Musculoskeletal (bone, muscle or joint) pain
  • Eczema
  • Upper respiratory tract infection
  • Sciatica
  • Pain in extremities
  • Posterior pain
  • Joint pain
  • Urinary tract infection
  • Constipation
  • Abdominal discomfort
  • Hair loss
  • Hypercholesterolemia (high cholesterol)
  • Cystitis
  • Nerve pain
  • Headache

Warning & Precautions:

Alcohol
CAUTION
Caution is advised when consuming alcohol with Denoclast Injection. Please consult your doctor.
Pregnancy
UNSAFE
Denoclast Injection is highly unsafe to use during pregnancy. Perceivek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Denoclast Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Denoclast Injection does not usually affect your ability to drive.
Kidney
CAUTION
Denoclast Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Denoclast Injection may be needed. Please consult your doctor.
Liver
CAUTION
Denoclast Injection should be used with caution in patients with severe liver disease. Dose adjustment of Denoclast Injection may be needed. Please consult your doctor.

FAQs:

How long can you stay on Denoclast Injection?

There is no optimal duration of treatment of osteoporosis with Denoclast Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denoclast Injection. Depending on this, the duration of taking Denoclast Injection is decided.

Does Denoclast Injection cause hair loss?

Affirmative, hair loss is a common side effect of Denoclast Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Is Denoclast Injection a chemotherapy drug?

Denoclast Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denoclast Injection makes the bones stronger and less likely to break.

How is Denoclast Injection given and how often?

Denoclast Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denoclast Injection.

Can Denoclast Injection be taken during pregnancy?

No, pregnant women should not take Denoclast Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denoclast Injection if you can become pregnant.

How should Denoclast Injection be stored?

Denoclast Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Does Denoclast Injection cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Denoclast Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denoclast Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

How long can you stay on Denoclast Injection?

There is no optimal duration of treatment of osteoporosis with Denoclast Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denoclast Injection. Depending on this, the duration of taking Denoclast Injection is decided.

Does Denoclast Injection cause hair loss?

Affirmative, hair loss is a common side effect of Denoclast Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Is Denoclast Injection a chemotherapy drug?

Denoclast Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denoclast Injection makes the bones stronger and less likely to break.

How is Denoclast Injection given and how often?

Denoclast Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denoclast Injection.

Can Denoclast Injection be taken during pregnancy?

No, pregnant women should not take Denoclast Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denoclast Injection if you can become pregnant.

How should Denoclast Injection be stored?

Denoclast Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Does Denoclast Injection cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Denoclast Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denoclast Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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