Calmsac Plus 0.25mg/20mg Tablet

Last Updated: March 25th, 2026

Calmsac Plus 0.25mg/20mg Tablet is a product of SAC Pharmaceuticals

Composition: Alprazolam (0.25mg) + Fluoxetine (20mg)

₹ 23.44

Note: MRP can vary depending up on batch!

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All Details About Calmsac Plus 0.25mg/20mg Tablet

Find out detailed description, uses, directions of use, side effects, warnings and precautions, frequently asked questions about Calmsac Plus 0.25mg/20mg Tablet

Description:

Tranquilsac Plus 0.25mg/20mg Tablet is a prescription medicine used in the treatment of depression. This combination medicine calms the brain by decreasing abnormal and excessive activity of the nerve cells. It also works by increasing some chemical messenger in the brain that improves mood.

Tranquilsac Plus 0.25mg/20mg Tablet is taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as this may cause nausea, anxiety, dysphoria, and agitation.

Some common side effects of this medicine include nausea, vomiting, diarrhea, confusion, and low sexual desire. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food and exercise regularly. However, weight loss can be managed by increasing food portions and consulting a dietitian. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses:

Depression

Directions For Use:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tranquilsac Plus 0.25mg/20mg Tablet may be taken with or without food.

Side Effects:

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Ordinary side effects of Tranquilsac Plus

Nausea
Vomiting
Diarrhea
Confusion
Memory impairment
Uncoordinated body movements
Drowsiness
Fatiguedness
Anorgasmia (decreased orgasm)
Delayed ejaculation
Low sexual desire

Warning & Precautions:

Alcohol

UNSAFE

It is unsafe to consume alcohol with Tranquilsac Plus 0.25mg/20mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

Tranquilsac Plus 0.25mg/20mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Tranquilsac Plus 0.25mg/20mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Tranquilsac Plus 0.25mg/20mg Tablet may cause side effects that could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Tranquilsac Plus 0.25mg/20mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CAUTION

Tranquilsac Plus 0.25mg/20mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

FAQs:

Written by:
Dr. T. Sharmila Krishna
M.B.B.S., MD (Biochemistry)

Reviewed by:
Dr. Sureshbabu Yadav
M.B.B.S., DIP.DIAB, F.R.S.H

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